The VKOR target for warfarin identified

被引：3

作者：

Le Bonniec, B ^{[1
]}

机构：

[1] INSERM, U428, UFR Sci Pharmaceut, F-75270 Paris 6, France

来源：

M S-MEDECINE SCIENCES | 2004年 / 20卷 / 05期

关键词：

D O I：

10.1051/medsci/2004205512

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：512 / 514

页数：3

共 9 条

[1]

BELL RG, 1978, FED PROC, V37, P2599

[2] Blood coagulation [J].

Dahlback, B .

LANCET, 2000, 355 (9215) :1627-1632

[3] Homozygosity mapping of a second gene locus for hereditary combined deficiency of vitamin K-dependent clotting factors to the centromeric region of chromosome 16 [J].

Fregin, A ;

Rost, S ;

Wolz, W ;

Krebsova, A ;

Muller, CR ;

Oldenburg, J .

BLOOD, 2002, 100 (09) :3229-3232

[4] A gene-anchored map position of the rat warfarin-resistance locus, Rw, and its orthologs in mice and humans [J].

Kohn, MH ;

Pelz, HJ .

BLOOD, 2000, 96 (05) :1996-1998

[5] Identification of the gene for vitamin K epoxide reductase [J].

Li, T ;

Chang, CY ;

Jin, DY ;

Lin, PJ ;

Khvorova, A ;

Stafford, DW .

NATURE, 2004, 427 (6974) :541-544

[6]

MANN KG, 1990, BLOOD, V76, P1

[7] Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2 [J].

Rost, S ;

Fregin, A ;

Ivaskevicius, V ;

Conzelmann, E ;

Hörtnagel, K ;

Pelz, HJ ;

Lappegard, K ;

Seifried, E ;

Scharrer, I ;

Tuddenham, EGD ;

Müller, CR ;

Strom, TM ;

Oldenburg, J .

NATURE, 2004, 427 (6974) :537-541

[8] Medicine: K is for koagulation [J].

Sadler, JE .

NATURE, 2004, 427 (6974) :493-494

[9] CLONING AND EXPRESSION OF THE CDNA FOR HUMAN GAMMA-GLUTAMYL CARBOXYLASE [J].

WU, SM ;

CHEUNG, WF ;

FRAZIER, D ;

STAFFORD, DW .

SCIENCE, 1991, 254 (5038) :1634-1636

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