Corticosteroids and Immune Suppressive Therapies in Horses

被引：31

作者：

Leclere, Mathilde ^{[1
]}

机构：

[1] Univ Montreal, Fac Med Vet, Dept Clin Sci, 3200 Sicotte, St Hyacinthe, PQ J2S 7C6, Canada

来源：

VETERINARY CLINICS OF NORTH AMERICA-EQUINE PRACTICE | 2017年 / 33卷 / 01期

关键词：

Azathioprine; Equine asthma; Glucocorticoids; Glucocorticosteroids; Immune-mediated; Immunomodulation; RECURRENT AIRWAY-OBSTRUCTION; INHALED FLUTICASONE PROPIONATE; BECLOMETHASONE DIPROPIONATE; PULMONARY-FUNCTION; LUNG-FUNCTION; MEDIATED THROMBOCYTOPENIA; TRIAMCINOLONE ACETONIDE; ADRENAL-GLAND; DEXAMETHASONE; HEAVES;

D O I：

10.1016/j.cveq.2016.11.008

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Immune suppressive therapies target exaggerated and deleterious responses of the immune system. Triggered by exogenous or endogenous factors, these improper responses can lead to immune or inflammatory manifestations, such as urticaria, equine asthma, or autoimmune and immune-mediated diseases. Glucocorticoids are the most commonly used immune suppressive drugs and the only ones supported by robust evidence of clinical efficacy in equine medicine. In some conditions, combining glucocorticoids with other pharmacologic and nonpharmacologic treatments, such as azathioprine, antihistamine, bronchodilators, environmental management, or desensitization, can help to decrease dosages and associated side effects.

引用

页码：17 / +

页数：12

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