The antiSMASH database version 3: increased taxonomic coverage and new query features for modular enzymes

被引：95

作者：

Blin, Kai ^{[1
]}

Shaw, Simon ^{[1
]}

Kautsar, Satria A. ^{[2
]}

Medema, Marnix H. ^{[2
]}

Weber, Tilmann ^{[1
]}

机构：

[1] Tech Univ Denmark, Novo Nordisk Fdn, Ctr Biosustainabil, DK-2800 Lyngby, Denmark

[2] Wageningen Univ, Bioinformat Grp, NL-6708 PB Wageningen, Netherlands

来源：

NUCLEIC ACIDS RESEARCH | 2021年 / 49卷 / D1期

基金：

新加坡国家研究基金会;

关键词：

TOOLS;

D O I：

10.1093/nar/gkaa978

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Microorganisms produce natural products that are frequently used in the development of antibacterial, antiviral, and anticancer drugs, pesticides, herbicides, or fungicides. In recent years, genome mining has evolved into a prominent method to access this potential. antiSMASH is one of the most popular tools for this task. Here, we present version 3 of the antiSMASH database, providing a means to access and query precomputed antiSMASH-5.2-detected biosynthetic gene clusters from representative, publicly available, high-quality microbial genomes via an interactive graphical user interface. In version 3, the database contains 147 517 high quality BGC regions from 388 archaeal, 25 236 bacterial and 177 fungal genomes and is available at https://antismash- db.secondarymetabolites.org/.

引用

页码：D639 / D643

页数：5

共 22 条

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