Low whole blood glutathione levels in pregnancies complicated by preeclampsia and diabetes

被引：17
作者：
Kharb, S [1 ]
机构：
[1] PT BD Sharma PGIMS, Dept Biochem, Rohtak, Haryana, India
来源：
CLINICA CHIMICA ACTA | 2000年 / 294卷 / 1-2期
关键词：
glutathione; diabetes; preeclampsia;
D O I：
10.1016/S0009-8981(99)00253-3
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Nineteen pregnancies with preeclampsia, 16 with diabetic preeclampsia and 29 control pregnancies were analyzed with regards to maternal total glutathione. In preeclampsia, maternal total glutathione levels were lower than in normal pregnancy (P < 0.001). Also, diabetic preeclamptics showed low total glutathione levels as compared to preeclampsia (P < 0.05) and control (P < 0.001). These findings indicate decreased detoxificating or free radical scavenging capacity in pregnancies complicated by preeclampsia and diabetes. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：179 / 183
页数：5
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