Metastable beta titanium alloys with both twinning (TWIP) and martensite transformation (TRIP) usually exhibit a low yield strength of between 200 and 500 MPa, but high strain hardening rate and large uniform elongation. Alloys that exhibit twinning on a single system provide a higher yield strength, but a lower strain hardening rate. Here, for the first time, we report a new alloy (Ti-7Mo-3Cr wt%) with both high yield strength (695 MPa) and high work hardening rate (similar to 1900 MPa) and a substantial 333% uniform elongation. The deformation mechanisms were systematically investigated using EBSD and TEM for samples strained to 1.3%, 5% and 16%. The high yield strength was achieved through initial deformation mechanisms of two twin systems, namely both {332}<113> and (112)<111> twinning. Importantly, the martensite transformation was suppressed at this stage of deformation. The combination of two twin systems, with approximately the same intensity, resulted in a high strain hardening rate (1600 MPa-1900 MPa), much greater compared to alloys that exhibit a single twin system. Moreover, the TRIP effect was observed at strains greater than 5%, which also contributed to the high strain hardening rate large uniform elongation. (C) 2018 Acta Materialia Inc. Published by Elsevier Ltd. This is an open access article under the CC BY license.