Determination of clinical significance of coagulase-negative staphylococci in blood cultures

被引：11

作者：

Karakullukcu, Asiye ^{[1
]}

Kuskucu, Mert Ahmet ^{[1
]}

Ergin, Sevgi ^{[1
]}

Aygun, Gokhan ^{[1
]}

Midilli, Kenan ^{[1
]}

Kucukbasmaci, Omer ^{[1
]}

机构：

[1] Istanbul Univ, Med Microbiol, Cerrahpasa Med Sch, Istanbul, Turkey

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2017年 / 87卷 / 03期

关键词：

Coagulase negative Staphylococci; Bacteremia; Blood culture; Contamination; RAPD-PCR; DISTINGUISH; BACTEREMIA; CRITERIA;

D O I：

10.1016/j.diagmicrobio.2016.12.006

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The aim of this study was to investigate the criteria used to distinguish coagulase-negative staphylococci (CoNS) bacteremia from contamination. We evaluated 162 adult patients with CoNS-positive blood cultures (BCs). Of the 162 patients, 35 (21.6%) had at least 2 positive BCs and 127 (78.4%) had a single positive BC. According to the Laboratory-Confirmed Bloodstream Infection (LCBI) criteria, 24 (14.8%) patients with the same species of CoNS had true bacteremia, and 138 (85.2%) patients had contaminants. Despite the detection of the same CoNS species, 9 of the 24 patients had different CoNS genotypes. Using clinical assessments, only 20 patients were diagnosed with true bacteremia, 8 of them had a single positive BC. We concluded that only using the LCBI criteria or clinical evaluations of a patient were not sufficient to distinguish CoNS bacteremia from contamination. Molecular identification should also be performed as a diagnostic laboratory parameter for CoNS bacteremia. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：291 / 294

页数：4

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