Obstructive sleep disordered breathing in 2-to 18-year-old children: diagnosis and management

被引:614
作者
Kaditis, Athanasios G. [1 ,2 ]
Alonso Alvarez, Maria Luz [3 ,4 ]
Boudewyns, An [5 ]
Alexopoulos, Emmanouel I. [6 ,7 ]
Ersu, Refika [8 ]
Joosten, Koen [9 ]
Larramona, Helena [10 ]
Miano, Silvia [11 ]
Narang, Indra [12 ]
Trang, Ha [13 ]
Tsaoussoglou, Marina [1 ,2 ]
Vandenbussche, Nele [14 ]
Villa, Maria Pia [15 ]
Van Waardenburg, Dick [16 ]
Weber, Silke [17 ]
Verhulst, Stijn [18 ]
机构
[1] Univ Athens, Sch Med, Dept Paediat 1, Paediat Pulmonol Unit, GR-11527 Athens, Greece
[2] Aghia Sophia Childrens Hosp, Athens, Greece
[3] Univ Hosp Burgos, Pulmonol, Multidisciplinary Sleep Unit, Burgos, Spain
[4] Burgos Fdn Hlth Res, CIBER Resp Dis CIBERES, Burgos, Spain
[5] Univ Antwerp, Univ Antwerp Hosp, Dept Otorhinolaryngol Head & Neck Surg, B-2020 Antwerp, Belgium
[6] Univ Thessaly, Sleep Disorders Lab, Sch Med, Larisa, Greece
[7] Larissa Univ Hosp, Larisa, Greece
[8] Marmara Univ, Div Paediat Pulmonol, Istanbul, Turkey
[9] Sophia Childrens Univ Hosp, Erasmus MC, Paediat Intens Care, Rotterdam, Netherlands
[10] Univ Autonoma Barcelona, Dept Paediat, Paediat Pulmonol Unit, Corp Sanitaria Parc Tauli,Hosp Sabadell, E-08193 Barcelona, Spain
[11] Civ Hosp Lugano, Sleep & Epilepsy Ctr, Neuroctr Southern Switzerland, Lugano, Switzerland
[12] Univ Toronto, Hosp Sick Children, Div Resp Med, Toronto, ON M5G 1X8, Canada
[13] Paris Diderot Univ, Robert Debre Univ Hosp, Paediat Sleep Ctr, EA REMES 7334, Paris, France
[14] Kempenhaeghe Fdn, Sleep Med Ctr, Heeze, Netherlands
[15] Univ Roma La Sapienza, S Andrea Hosp, Pediat Sleep Dis Ctr, Child Neurol,NESMOS Dept,Sch Med & Psychol, I-00185 Rome, Italy
[16] Maastricht Univ, Dept Paediat, Med Ctr, Paediat Intens Care Unit, NL-6200 MD Maastricht, Netherlands
[17] Sao Paulo State Univ UNESP, Botucatu Med Sch, Dept Ophthalmol Otolaryngol & Head & Neck Surg, Sao Paulo, Brazil
[18] Univ Antwerp Hosp, Dept Paediat, Edegem, Belgium
关键词
POSITIVE AIRWAY PRESSURE; QUALITY-OF-LIFE; PRADER-WILLI-SYNDROME; RAPID MAXILLARY EXPANSION; AMBULATORY BLOOD-PRESSURE; THE TUCSON CHILDRENS; POLYGRAPHIC RESPIRATORY EVENTS; DEFICIT HYPERACTIVITY DISORDER; LEUKOTRIENE MODIFIER THERAPY; EXCESSIVE DAYTIME SLEEPINESS;
D O I
10.1183/13993003.00385-2015
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
This document summarises the conclusions of a European Respiratory Society Task Force on the diagnosis and management of obstructive sleep disordered breathing (SDB) in childhood and refers to children aged 2-18 years. Prospective cohort studies describing the natural history of SDB or randomised, double-blind, placebo-controlled trials regarding its management are scarce. Selected evidence (362 articles) can be consolidated into seven management steps. SDB is suspected when symptoms or abnormalities related to upper airway obstruction are present (step 1). Central nervous or cardiovascular system morbidity, growth failure or enuresis and predictors of SDB persistence in the long-term are recognised (steps 2 and 3), and SDB severity is determined objectively preferably using polysomnography (step 4). Children with an apnoea-hypopnoea index (AHI) >5 episodes.h(-1), those with an AHI of 1-5 episodes.h(-1) and the presence of morbidity or factors predicting SDB persistence, and children with complex conditions (e.g. Down syndrome and Prader-Willi syndrome) all appear to benefit from treatment (step 5). Treatment interventions are usually implemented in a stepwise fashion addressing all abnormalities that predispose to SDB (step 6) with re-evaluation after each intervention to detect residual disease and to determine the need for additional treatment (step 7).
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页码:69 / 94
页数:26
相关论文
共 268 条
[1]   Differences in Overnight Polysomnography Scores Using the Adult and Pediatric Criteria for Respiratory Events in Adolescents [J].
Accardo, Jennifer A. ;
Shults, Justine ;
Leonard, Mary B. ;
Traylor, Joel ;
Marcus, Carole L. .
SLEEP, 2010, 33 (10) :1333-1339
[2]   Sleep, breathing, and cephalometrics in older children and young adults .1. Normative values [J].
Acebo, C ;
Millman, RP ;
Rosenberg, C ;
Cavallo, A ;
Carskadon, MA .
CHEST, 1996, 109 (03) :664-672
[3]   Central sleep apnea and associated Chiari malformation in children with syndromic craniosynostosis: treatment and outcome data from a supraregional national craniofacial center [J].
Addo, Nii K. ;
Javadpour, Sheila ;
Kandasamy, Jothy ;
Sillifant, Paul ;
May, Paul ;
Sinha, Ajay .
JOURNAL OF NEUROSURGERY-PEDIATRICS, 2013, 11 (03) :296-301
[4]   Respiratory events and obstructive sleep apnea in children with achondroplasia: investigation and treatment outcomes [J].
Afsharpaiman, Shahla ;
Sillence, David O. ;
Sheikhvatan, Mehrdad ;
Ault, Jenny E. ;
Waters, Karen .
SLEEP AND BREATHING, 2011, 15 (04) :755-761
[5]   Obstructive sleep apnea in Treacher Collins syndrome [J].
Akre, Harriet ;
Overland, Britt ;
Asten, Pamela ;
Skogedal, Nina ;
Heimdal, Ketil .
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2012, 269 (01) :331-337
[6]   Longitudinal Evaluation of Sleep-Disordered Breathing in Children with Prader-Willi Syndrome during 2 Years of Growth Hormone Therapy [J].
Al-Saleh, Suhail ;
Al-Naimi, Amal ;
Hamilton, Jill ;
Zweerink, Allison ;
Iaboni, Andrea ;
Narang, Indra .
JOURNAL OF PEDIATRICS, 2013, 162 (02) :263-+
[7]   Nocturnal enuresis is associated with moderate-to-severe obstructive sleep apnea in children with snoring [J].
Alexopoulos, Emmanouel I. ;
Malakasioti, Georgia ;
Varlami, Vasiliki ;
Miligkos, Michail ;
Gourgoulianis, Konstantinos ;
Kaditis, Athanasios G. .
PEDIATRIC RESEARCH, 2014, 76 (06) :555-559
[8]   Parental History of Adenotonsillectomy Is Associated with Obstructive Sleep Apnea Severity in Children with Snoring [J].
Alexopoulos, Emmanouel I. ;
Charitos, George ;
Malakasioti, Georgia ;
Varlami, Vasiliki ;
Gourgoulianis, Konstantinos ;
Zintzaras, Elias ;
Kaditis, Athanasios G. .
JOURNAL OF PEDIATRICS, 2014, 164 (06) :1352-1357
[9]   Obstructive Sleep Apnea in Obese Community-Dwelling Children: The NANOS Study [J].
Alonso-Alvarez, Maria Luz ;
Cordero-Guevara, Jose Aurelio ;
Teran-Santos, Joaquin ;
Gonzalez-Martinez, Monica ;
Jurado-Luque, Maria Jose ;
Corral-Penafiel, Jaime ;
Duran-Cantolla, Joaquin ;
Kheirandish-Gozal, Leila ;
Gozal, David .
SLEEP, 2014, 37 (05) :943-949
[10]   Sleep-disordered breathing in children with Chiari malformation type II and myelomeningocele [J].
Alsaadi, Muslim M. ;
Iqbal, Shaikh M. ;
Elgamal, Essam A. ;
Gozal, David .
PEDIATRICS INTERNATIONAL, 2012, 54 (05) :623-626