Glucosamine Hydrochloride Functionalized Water-Soluble Conjugated Polyfluorene: Synthesis, Characterization, and Interactions with DNA

被引:25
作者
Chen, Oi [1 ]
Cheng, Qian-Yi [1 ,2 ]
Zhao, Yan-Chao [1 ,2 ]
Han, Bao-Hang [1 ]
机构
[1] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China
[2] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
基金
美国国家科学基金会;
关键词
conjugated polymer; DNA; fluorescence; glucosamine hydrochloride; sensors; SENSITIVE DETECTION; HIGH-EFFICIENCY; GENE DELIVERY; POLYELECTROLYTES; FLUORESCENT; GLYCOPOLYMERS; POLYMERS; PREPOLYMERIZATION; ETHYNYLENE); COMPLEXES;
D O I
10.1002/marc.200900226
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Novel glucosamine hydrochloride functionalized water-soluble conjugated polyfluorene was easily synthesized through Cu(I)-catalyzed azide/alkyne "click" ligation and Suzuki coupling polymerization. The water-solubility and biocompatibility of the polymer were improved after grarting glucosamine hydrochloride to the side chains of the conjugated polymer. As a fluorescent model system of chitosan, its interaction with single-stranded DNA was studied by spectrofluorometric titration.
引用
收藏
页码:1651 / 1655
页数:5
相关论文
共 52 条
[11]   Fluorescent conjugated polyelectrolytes for biomacromolecule detection [J].
Feng, Fude ;
He, Fang ;
An, Lingling ;
Wang, Shu ;
Li, Yuhang ;
Zhu, Daoben .
ADVANCED MATERIALS, 2008, 20 (15) :2959-2964
[12]   Cationic Conjugated Polyelectrolyte Electron Injection Layers: Effect of Halide Counterions [J].
Garcia, Andres ;
Brzezinski, Jacek Z. ;
Nguyen, Thuc-Quyen .
JOURNAL OF PHYSICAL CHEMISTRY C, 2009, 113 (07) :2950-2954
[13]   DNA hybridization detection with water-soluble conjugated polymers and chromophore-labeled single-stranded DNA [J].
Gaylord, BS ;
Heeger, AJ ;
Bazan, GC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (04) :896-900
[14]   Optical detection of DNA and proteins moth cationic polythiophenes [J].
Ho, Hoang-A. ;
Najari, Ahmed ;
Leclerc, Mario .
ACCOUNTS OF CHEMICAL RESEARCH, 2008, 41 (02) :168-178
[15]   High-efficiency, environment-friendly electroluminescent polymers with stable high work function metal as a cathode: Green- and yellow-emitting conjugated polyfluorene polyelectrolytes and their neutral precursors [J].
Huang, F ;
Hou, LT ;
Wu, HB ;
Wang, XH ;
Shen, HL ;
Cao, W ;
Yang, W ;
Cao, Y .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2004, 126 (31) :9845-9853
[16]   Novel electroluminescent conjugated polyelectrolytes based on polyfluorene [J].
Huang, F ;
Wu, HB ;
Wang, D ;
Yang, W ;
Cao, Y .
CHEMISTRY OF MATERIALS, 2004, 16 (04) :708-716
[17]   Synthesis and Characterization of Regioregular Water-Soluble 3,4-Propylenedioxythiophene Derivative and Its Application in the Fabrication of High-Contrast Solid-State Electrochromic Devices [J].
Jain, Vaibhav ;
Sahoo, Rabindra ;
Mishra, Sarada P. ;
Sinha, Jasmine ;
Montazami, Reza ;
Yochum, Hank M. ;
Heflin, James R. ;
Kumar, Anil .
MACROMOLECULES, 2009, 42 (01) :135-140
[18]   Variable-Band-Gap Poly(arylene ethynylene) Conjugated Polyelectrolytes Adsorbed on Nanocrystalline TiO2: Photocurrent Efficiency as a Function of the Band Gap [J].
Jiang, Hui ;
Zhao, Xiaoyong ;
Shelton, Abigail H. ;
Lee, Seoung Ho ;
Reynolds, John R. ;
Schanze, Kirk S. .
ACS APPLIED MATERIALS & INTERFACES, 2009, 1 (02) :381-387
[19]   Sensing of lead ions by a carboxylate-substituted PPE: Multivalency effects [J].
Kim, IB ;
Dunkhorst, A ;
Gilbert, J ;
Bunz, UHF .
MACROMOLECULES, 2005, 38 (11) :4560-4562
[20]   Water soluble photo- and electroluminescent alkoxy-sulfonated poly(p-phenylenes) synthesized via palladium catalysis [J].
Kim, S ;
Jackiw, J ;
Robinson, E ;
Schanze, KS ;
Reynolds, JR ;
Baur, J ;
Rubner, MF ;
Boils, D .
MACROMOLECULES, 1998, 31 (04) :964-974