Diaphragm pacing restores olfaction in tetraplegia

被引:34
作者
Adler, D. [1 ,2 ,4 ,5 ]
Gonzalez-Bermejo, J. [1 ,2 ,4 ]
Duguet, A. [1 ,2 ,4 ]
Demoule, A. [1 ,2 ,4 ]
Le Pimpec-Barthes, F. [3 ]
Hurbault, A. [1 ,2 ]
Morelot-Panzini, C. [1 ,2 ,4 ]
Similowski, T. [1 ,2 ,4 ]
机构
[1] Grp Hosp Pitie Salpetriere, AP HP, Serv Pneumol & Reanimat, F-75651 Paris 13, France
[2] Grp Hosp Pitie Salpetriere, Ctr Stimulta Phren Implantee, F-75651 Paris 13, France
[3] Hop Europeen Georges Pompidou, AP HP, Serv Chirurg Thorac, Paris, France
[4] Univ Paris 06, ER UPMC 10, Paris, France
[5] Univ Geneva, Hop Cantonal, Serv Pneumol, CH-1211 Geneva, Switzerland
关键词
Phrenic stimulation; quality of life; spinal cord injury; tracheotomy; ventilator-dependency; SPINAL-CORD-INJURY; OF-PENNSYLVANIA SMELL; VENTILATOR-DEPENDENT PATIENTS; TRACHEOSTOMY SPEAKING VALVE; IDENTIFICATION TEST; LIFE; STIMULATION; SATISFACTION; LARYNGECTOMY; SPEECH;
D O I
10.1183/09031936.00177708
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
High cervical spinal cord injuries induce extreme handicap and tactile isolation. Tracheotomised tetraplegic patients are also bound to be olfaction deprived. By restoring negative pressure inspiration, diaphragm pacing (DP) should improve olfaction. We tested olfaction in 10 consecutive tetraplegics during positive pressure mechanical ventilation and DP, using the University of Pennsylvania Smell Identification Test (UPSIT). Quality of life was assessed using the Satisfaction with Life Scale (SWLS). Self-perceived benefits of DP were studied using an in-house questionnaire. Olfaction was very poor during positive pressure mechanical ventilation (UPSIT, mean +/- SD 17.1 +/- 6.4, anosmia or severe microsmia). It improved during DP (35.2 +/- 1.9, normosmia or mild microsmia; p<0.0001) and SWLS was 18.5 +/- 4.2. Nine patients stated that DP had improved their quality of life. This was driven by better mobility (ranked first), improved self-image and relationships with others (ranked second), improved olfaction and better feeling of security (both ranked third). Improved olfaction is among the benefits of DID and should be mentioned to patients considered for this therapy. Furthermore, attention to olfaction is warranted in tracheotomised ventilator-dependent patients, as a putative path towards improvement of quality of life.
引用
收藏
页码:365 / 370
页数:6
相关论文
共 23 条
[1]   Psychological or physiological - Why are tetraplegic patients content? [J].
Abrantes-Pais, Fatima de N. ;
Friedman, Joyce K. ;
Lovallo, William R. ;
Ross, Elliott D. .
NEUROLOGY, 2007, 69 (03) :261-267
[2]  
Creasey G, 1996, J REHABIL RES DEV, V33, P123
[3]   POPULATION-BASED NORMS FOR THE MINI-MENTAL-STATE-EXAMINATION BY AGE AND EDUCATIONAL-LEVEL [J].
CRUM, RM ;
ANTHONY, JC ;
BASSETT, SS ;
FOLSTEIN, MF .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1993, 269 (18) :2386-2391
[4]  
DEEMS DA, 1991, ARCH OTOLARYNGOL, V117, P519
[5]   THE SATISFACTION WITH LIFE SCALE [J].
DIENER, E ;
EMMONS, RA ;
LARSEN, RJ ;
GRIFFIN, S .
JOURNAL OF PERSONALITY ASSESSMENT, 1985, 49 (01) :71-75
[6]   Correlates of life satisfaction among persons with spinal cord injury [J].
Dijkers, MPJM .
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 1999, 80 (08) :867-876
[7]   Restoration of respiratory muscle function following spinal cord injury - Review electrical and magnetic stimulation techniques [J].
DiMarco, AF .
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY, 2005, 147 (2-3) :273-287
[8]  
DIMARCO AF, 2006, PRINCIPLES PRACTICES, P1263
[9]   DEVELOPMENT OF THE UNIVERSITY-OF-PENNSYLVANIA SMELL IDENTIFICATION TEST - A STANDARDIZED MICROENCAPSULATED TEST OF OLFACTORY FUNCTION [J].
DOTY, RL ;
SHAMAN, P ;
DANN, M .
PHYSIOLOGY & BEHAVIOR, 1984, 32 (03) :489-502
[10]   INTERNAL CONSISTENCY RELIABILITY OF THE FRACTIONATED AND WHOLE UNIVERSITY-OF-PENNSYLVANIA SMELL IDENTIFICATION TEST [J].
DOTY, RL ;
FRYE, RE ;
AGRAWAL, U .
PERCEPTION & PSYCHOPHYSICS, 1989, 45 (05) :381-384