Bosentan increases serum IL-12 levels in systemic sclerosis patients with pulmonary arterial hypertension

被引：8
作者：
Hamaguchi, Yasuhito [1 ]
Fujimoto, Manabu [1 ]
Hasegawa, Minoru [1 ]
Matsushita, Takashi [1 ]
Takehara, Kazuhiko [1 ]
机构：
[1] Kanazawa Univ, Grad Sch Med Sci, Dept Dermatol, Kanazawa, Ishikawa 9208641, Japan
来源：
JOURNAL OF DERMATOLOGICAL SCIENCE | 2009年 / 55卷 / 01期
关键词：
Systemic sclerosis; Pulmonary arterial hypertension; IL-12; Bosentan; ENDOTHELIN-1; INTERLEUKIN-12; CYTOKINES;
D O I：
10.1016/j.jdermsci.2009.02.013
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：66 / 67
页数：2
相关论文
共 10 条
  • [1] PRELIMINARY CRITERIA FOR THE CLASSIFICATION OF SYSTEMIC-SCLEROSIS (SCLERODERMA)
    不详
    [J]. ARTHRITIS AND RHEUMATISM, 1980, 23 (05): : 581 - 590
  • [2] INCREASED LEVELS OF ENDOTHELIN-1 IN BRONCHOALVEOLAR LAVAGE FLUID FROM PATIENTS WITH SYSTEMIC-SCLEROSIS CONTRIBUTE TO FIBROBLAST MITOGENIC ACTIVITY IN-VITRO
    CAMBREY, AD
    HARRISON, NK
    DAWES, KE
    SOUTHCOTT, AM
    BLACK, CM
    DUBOIS, RM
    LAURENT, GJ
    MCANULTY, RJ
    [J]. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1994, 11 (04) : 439 - 445
  • [3] Endothelin-1 and endothelin-4 stimulate monocyte production of cytokines
    Cunningham, ME
    Huribal, M
    Bala, RJ
    McMillen, MA
    [J]. CRITICAL CARE MEDICINE, 1997, 25 (06) : 958 - 964
  • [4] Pathogenesis of systemic sclerosis: Altered B cell function is the key linking systemic autoimmunity and tissue fibrosis
    Hasegawa, M
    Fujimoto, M
    Takehara, K
    Sato, S
    [J]. JOURNAL OF DERMATOLOGICAL SCIENCE, 2005, 39 (01) : 1 - 7
  • [5] ENDOTHELIN, AN ENDOTHELIAL-DEPENDENT VASOCONSTRICTOR IN SCLERODERMA - ENHANCED PRODUCTION AND PROFIBROTIC ACTION
    KAHALEH, MB
    [J]. ARTHRITIS AND RHEUMATISM, 1991, 34 (08): : 978 - 983
  • [6] INCREASED ENDOTHELIN-1 PRODUCTION IN FIBROBLASTS DERIVED FROM PATIENTS WITH SYSTEMIC-SCLEROSIS
    KAWAGUCHI, Y
    SUZUKI, K
    HARA, M
    HIDAKA, T
    ISHIZUKA, T
    KAWAGOE, M
    NAKAMURA, H
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 1994, 53 (08) : 506 - 510
  • [7] Matsushita T, 2006, J RHEUMATOL, V33, P275
  • [8] MCMILLEN MA, 1995, J AM COLL SURGEONS, V180, P621
  • [9] Bosentan therapy for pulmonary arterial hypertension
    Rubin, LJ
    Badesch, DB
    Barst, RJ
    Galiè, N
    Black, CM
    Keogh, A
    Pulido, T
    Frost, A
    Roux, S
    Leconte, I
    Landzberg, M
    Simonneau, G
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (12) : 896 - 903
  • [10] INTERLEUKIN-12 - A CYTOKINE PRODUCED BY ANTIGEN-PRESENTING CELLS WITH IMMUNOREGULATORY FUNCTIONS IN THE GENERATION OF T-HELPER CELLS TYPE-1 AND CYTOTOXIC LYMPHOCYTES
    TRINCHIERI, G
    [J]. BLOOD, 1994, 84 (12) : 4008 - 4027
1