Trophoblastic Disease Review for Diagnosis and Management A Joint Report From the International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup

被引：90

作者：

Mangili, Giorgia ^{[1
]}

Lorusso, Domenica ^{[2
]}

Brown, Jubilee ^{[3
]}

Pfisterer, Jacobus ^{[4
]}

Massuger, Leon ^{[5
]}

Vaughan, Michelle ^{[6
]}

Ngan, Hextan Y. S. ^{[7
]}

Golfier, Francois ^{[8
]}

Sekharan, Paradan K. ^{[9
]}

Charry, Rafael Cortes ^{[10
]}

Poveda, Andres ^{[11
]}

Kim, Jae-Weon ^{[12
]}

Xiang, Yang ^{[13
,14
]}

Berkowtiz, Ross ^{[15
]}

Seckl, Michael J. ^{[16
,17
]}

机构：

[1] IRCCS San Raffaele Hosp, Dept Gynecol & Obstet, Milan, Italy

[2] Univ Cattolica Sacro Cuore, Dept Gynecol Oncol, I-00168 Rome, Italy

[3] Univ Texas MD Anderson Canc Ctr, Gynecol Oncol Grp, Houston, TX 77030 USA

[4] AGO Study Grp, Gynecol Oncol Ctr, Kiel, Germany

[5] Radboud Univ Nijmegen Med Ctr, Dept Obstet & Gynaecol, Nijmegen, Netherlands

[6] ANZGOG, Camperdown, NSW, Australia

[7] Univ Hong Kong, Queen Mary Hosp, Dept Obstet & Gynecol, Hong Kong, Hong Kong, Peoples R China

[8] Hosp Civils Lyon, Ctr Reference Malad Trophoblast, Lyon, France

[9] Coll Med, Inst Maternal & Child Hlth, Dept Obstet & Gynecol, Calicut, Kerala, India

[10] Cent Univ Venezuela, Univ Hosp Caracas, GTD Unit, Caracas, Venezuela

[11] Fdn Inst Valenciano Oncol, Spanish Ovarian Canc Res Grp GEICO, Valencia, Spain

[12] Seoul Natl Univ Hosp, Korean Gynaecol Oncol Grp, Seoul 110744, South Korea

[13] Chinese Acad Med Sci, Dept Obstet & Gynecol, Peking Union Med Coll Hosp, Beijing 100730, Peoples R China

[14] Peking Union Med Coll, Beijing 100021, Peoples R China

[15] Harvard Univ, Brigham & Womens Hosp, Div Gynecol Oncol, Dept Obstet & Gynecol,Dana Farber Canc Inst,Sch M, Boston, MA 02115 USA

[16] Charing Cross Campus Imperial Coll London, Charing Cross Trophoblast Dis Ctr, Dept Histopathol, London, England

[17] Charing Cross Campus Imperial Coll London, Charing Cross Trophoblast Dis Ctr, Dept Med Oncol, London, England

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 2014年 / 24卷 / 09期

关键词：

Gestational trophoblastic disease; Management; Diagnosis; Review; SINGLE-AGENT METHOTREXATE; FACTOR SCORING SYSTEM; MOLAR PREGNANCY; NEOPLASIA; CHEMOTHERAPY; RESISTANCE; ETOPOSIDE; TUMORS; LUNG; HCG;

D O I：

10.1097/IGC.0000000000000294

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: The objective of this study was to provide a consensus review on gestational trophoblastic disease diagnosis and management from the combined International Society for the Study of Trophoblastic Disease, European Organisation for the Treatment of Trophoblastic Disease, and the Gynecologic Cancer InterGroup. Methods: A joint committee representing various groups reviewed the literature obtained from PubMed searches. Results and Conclusions: Guidelines were constructed on the basis of literature review. After initial diagnosis in local centers, centralization of pathology review and ongoing care is recommended to achieve the best outcomes.

引用

页码：S109 / S116

页数：8

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