Tight junctions: Closing in on the seal

被引：42

作者：

Anderson, JM

Van Itallie, CM

机构：

[1] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06580 USA

[2] Yale Univ, Sch Med, Dept Cell Biol, New Haven, CT 06580 USA

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 24期

关键词：

D O I：

10.1016/S0960-9822(00)80105-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The claudins have recently been identified as a large family of transmembrane proteins located at tight junctions between epithelial cells; they create the paracellular diffusion barrier and, surprisingly, may also confer channel-like selectivity for passage of solutes through the tissue barrier. (C) 1999 Elsevier Science Ltd. All rights reserved.

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收藏

页码：R922 / R924

页数：3

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