Enhanced Photothermal Effect of Plasmonic Nanoparticles Coated with Reduced Graphene Oxide

被引:285
作者
Lim, Dong-Kwon [1 ,2 ,3 ]
Barhoumi, Aoune [1 ,2 ]
Wylie, Ryan G. [1 ,2 ]
Reznor, Gally [1 ]
Langer, Robert S. [2 ]
Kohane, Daniel S. [1 ]
机构
[1] Harvard Univ, Sch Med, Childrens Hosp Boston, Dept Anesthesiol,Div Crit Care Med,Lab Biomat & D, Boston, MA 02115 USA
[2] MIT, David H Koch Inst Integrat Canc Res, Cambridge, MA 02139 USA
[3] Chonbuk Natl Univ, Dept BIN Fus Technol, Jeonju 561756, South Korea
关键词
Enhanced Photothermal Effect; Plasmonic Nanoparticle; Gold Nanoshell; Gold Nanorod; Reduced Graphene; r-GO Coated Gold Nanoparticle; Cell Viability; GOLD NANOPARTICLES; CARBON NANOTUBES; RAMAN-SCATTERING; THERAPY; NANORODS; DELIVERY; NANOSTRUCTURES; NANOSHELLS; RELEASE; CELLS;
D O I
10.1021/nl4014315
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report plasmonic gold nanoshells and nanorods coated with reduced graphene oxide that produce an enhanced photothermal effect when stimulated by near-infrared (NIR) light. Electrostatic interactions between nanosized graphene oxide and gold nanoparticles followed by in situ chemical reduction generated reduced graphene oxide-coated nanoparticles; the coating was demonstrated using Raman and HR-TEM. Reduced graphene oxide-coated gold nanoparticles showed enhanced photothermal effect compared to noncoated or nonreduced graphene oxide-coated gold nanoparticles. Reduced graphene oxide-coated gold nanoparticles killed cells more rapidly than did noncoated or nonreduced graphene oxide-coated gold nanoparticles.
引用
收藏
页码:4075 / 4079
页数:5
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