Gestational programming of offspring obesity/hypertension

被引：12
作者：
Novak, Donald A. [1 ]
Desai, Mina
Ross, Michael G.
机构：
[1] Univ Florida, Coll Med, Dept Pediat, Gainesville, FL 32610 USA
[2] Univ Calif Los Angeles, Harbor Med Ctr, Geffen Sch Med, Dept Obstet & Gynecol, Los Angeles, CA 90024 USA
来源：
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE | 2006年 / 19卷 / 10期
关键词：
obesity; hypertension; IUGR; development; fetal origins;
D O I：
10.1080/14767050600708233
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The intrauterine milieu impacts fetal growth directly during gestation. It is now clear, however, that postnatal phenotype is also influenced by prenatal conditions. A variety of disorders in the adult have been linked to fetal size at birth; these include glucose intolerance, cardiovascular disease, and the subjects of this review, obesity and hypertension. We will review recent data regarding these associations and the pathophysiologic mechanisms underlying them in humans as well as in animal models.
引用
收藏
页码：591 / 599
页数：9
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