Red blood cell deformability in multiple myeloma

被引：9

作者：

Caimi, Gregorio ^{[1
]}

Carlisi, Melania ^{[1
]}

Montana, Maria ^{[1
]}

Galla, Eleonora ^{[1
]}

Hopps, Eugenia ^{[1
]}

Lo Presti, Rosalia ^{[1
]}

Siragusa, Sergio ^{[1
]}

机构：

[1] Univ Palermo, Dipartmento Biomed Med Interna & Specialist, Palermo, Italy

来源：

CLINICAL HEMORHEOLOGY AND MICROCIRCULATION | 2018年 / 69卷 / 1-2期

关键词：

Multiple myeloma; erythrocyte deformability; microcirculation; NOCTURNAL HEMOGLOBINURIA-PHENOTYPE; ATOMIC-FORCE MICROSCOPY; FATTY-ACID SYNTHASE; HYPERVISCOSITY SYNDROME; IGA MYELOMA; ERYTHROCYTES; POPULATIONS; ANEMIA; PATHOGENESIS; ASSOCIATION;

D O I：

10.3233/CH-189121

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The aim of this study was the evaluation of the erythrocyte deformability in multiple myeloma (MM). We enrolled 29 MM patients and we evaluated, on fasting venous blood, the erythrocyte deformability, expressed as elongation index, and examined using the diffractometric method. By comparing normal controls and MM patients, a significant decrease in erythrocyte deformability, especially at low shear stresses, was found. In this research paper we evaluated all the hypothesis for a possible explanation of the behaviour of red blood cell deformability in MM, even considering how the alteration of erythrocyte deformability worsens the microcirculatory flow in these patients in association with the marked increase in plasma viscosity.

引用

页码：233 / 238

页数：6

共 50 条

[21] Assessment of Red Blood Cell Distribution Width and Multiple Myeloma in a Guangxi Population: a Retrospective Study
Huang, Chunni
Wei, Huiping
Lan, Fang
Lu, Yu
Li, Shan
Qin, Xue
CLINICAL LABORATORY, 2019, 65 (03) : 297 - 303
[22] Prognostic Value of Elevated Red Blood Cell Distribution Width in Chinese Patients with Multiple Myeloma
Meng, Shan
Ma, Zhuo
Lu, Chenyang
Liu, Hailing
Tu, Honglei
Zhang, Wanggang
Zhou, Fuling
ANNALS OF CLINICAL AND LABORATORY SCIENCE, 2017, 47 (03) : 282 - 290
[23] Deformability of Heterogeneous Red Blood Cells in Aging and Related Pathologies
Prudinnik, Dmitry S.
Kussanova, Aigul
Vorobjev, Ivan A.
Tikhonov, Alexander
Ataullakhanov, Fazly I.
Barteneva, Natasha S.
AGING AND DISEASE, 2024,
[24] On the Effects of Reactive Oxygen Species and Nitric Oxide on Red Blood Cell Deformability
Diederich, Lukas
Suvorava, Tatsiana
Sansone, Roberto
Keller, T. C. Stevenson
Barbarino, Frederik
Sutton, Thomas R.
Kramer, Christian M.
Lueckstaedt, Wiebke
Isakson, Brant E.
Gohlke, Holger
Feelisch, Martin
Kelm, Malte
Cortese-Krott, Miriam M.
FRONTIERS IN PHYSIOLOGY, 2018, 9
[25] Heterogeneous Red Blood Cell Adhesion and Deformability in Sickle Cell Disease
Alapan, Yunus
Little, Jane A.
Gurkan, Umut A.
SCIENTIFIC REPORTS, 2014, 4
[26] Pre-treatment red blood cell distribution width provides prognostic information in multiple myeloma
Zhou, Di
Xu, Peipei
Peng, Miaoxin
Shao, Xiaoyan
Wang, Miao
Ouyang, Jian
Chen, Bing
CLINICA CHIMICA ACTA, 2018, 481 : 34 - 41
[27] The influence of sevoflurane anesthesia on the rat red blood cell deformability
Aydogan, Sami
Yerer, Mukerrem Betul
Comu, Faruk Metin
Arslan, Mustafa
Gunes-Ekinci, Isin
Unal, Yusuf
Kurtipek, Omer
CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2006, 35 (1-2) : 297 - 300
[28] Reduced red blood cell deformability in Plasmodium knowlesi malaria
Barber, Bridget E.
Russell, Bruce
Grigg, Matthew J.
Zhang, Rou
William, Timothy
Amir, Amirah
Lau, Yee Ling
Chatfield, Mark D.
Dondorp, Arjen M.
Anstey, Nicholas M.
Yeo, Tsin W.
BLOOD ADVANCES, 2018, 2 (04) : 433 - 443
[29] Asymptomatic elevation of the hyperchromic red blood cell subpopulation is associated with decreased red cell deformability
Deuel, Jeremy W.
Lutz, Hans U.
Misselwitz, Benjamin
Goede, Jeroen S.
ANNALS OF HEMATOLOGY, 2012, 91 (09) : 1427 - 1434
[30] Nitric oxide bioavailability for red blood cell deformability in the microcirculation: A review of recent progress
Kobayashi, Jun
Ohtake, Kazuo
Murata, Isamu
Sonoda, Kunihiro
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2022, 129 : 25 - 29

← 1 2 3 4 5 →