Are Macrophages the Foot Soldiers in the War Waged by Aldosterone Against the Heart?

被引:6
作者
Dorrance, Anne M. [1 ]
机构
[1] Michigan State Univ, Dept Pharmacol & Toxicol, E Lansing, MI 48824 USA
关键词
MINERALOCORTICOID RECEPTOR; CARDIAC FIBROSIS;
D O I
10.1161/HYPERTENSIONAHA.109.135855
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
引用
收藏
页码:451 / 453
页数:3
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共 10 条
[1]   Functional mineralocorticoid receptors in human vascular endothelial cells regulate intercellular adhesion molecule-1 expression and promote leukocyte adhesion [J].
Caprio, Massimiliano ;
Newfell, Brenna G. ;
la Sala, Andrea ;
Baur, Wendy ;
Fabbri, Andrea ;
Rosano, Giuseppe ;
Mendelsohn, Michael E. ;
Jaffe, Iris Z. .
CIRCULATION RESEARCH, 2008, 102 (11) :1359-1367
[2]   Immediate mineralocorticoid receptor blockade improves myocardial infarct healing by modulation of the inflammatory response [J].
Fraccarollo, Daniela ;
Galuppo, Paolo ;
Schraut, Susanne ;
Kneitz, Susanne ;
van Rooijen, Nico ;
Ertl, Georg ;
Bauersachs, Johann .
HYPERTENSION, 2008, 51 (04) :905-914
[3]   RALES, EPHESUS and redox [J].
Funder, JW .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2005, 93 (2-5) :121-125
[4]   Resistance artery remodeling in deoxycorticosterone acetate-salt hypertension is dependent on vascular inflammation: evidence from m-CSF-deficient mice [J].
Ko, Eun A. ;
Amiri, Farhad ;
Pandey, Nihar R. ;
Javeshghani, Danesh ;
Leibovitz, Eyal ;
Touyz, Rhian M. ;
Schiffrin, Ernesto L. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2007, 292 (04) :H1789-H1795
[5]   Glucocorticoids exert opposing effects on macrophage function dependent on their concentration [J].
Lim, Hee-Young ;
Mueller, Nora ;
Herold, Marco J. ;
van den Brandt, Jens ;
Reichardt, Holger M. .
IMMUNOLOGY, 2007, 122 (01) :47-53
[6]   IMMUNOHISTOCHEMICAL AND BIOCHEMICAL-EVIDENCE FOR A CARDIOVASCULAR MINERALOCORTICOID RECEPTOR [J].
LOMBES, M ;
OBLIN, ME ;
GASC, JM ;
BAULIEU, EE ;
FARMAN, N ;
BONVALET, JP .
CIRCULATION RESEARCH, 1992, 71 (03) :503-510
[7]   New vistas on macrophage differentiation and activation [J].
Mantovani, Alberto ;
Sica, Antonio ;
Locati, Massimo .
EUROPEAN JOURNAL OF IMMUNOLOGY, 2007, 37 (01) :14-16
[8]   Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure [J].
Rickard, Amanda J. ;
Morgan, James ;
Tesch, Greg ;
Funder, John W. ;
Fuller, Peter J. ;
Young, Morag J. .
HYPERTENSION, 2009, 54 (03) :537-U180
[9]   Eplerenone, but not steroid withdrawal, reverses cardiac fibrosis in deoxycorticosterone/salt-treated rats [J].
Young, M ;
Funder, JW .
ENDOCRINOLOGY, 2004, 145 (07) :3153-3157
[10]   Mineralocorticoid action and sodium-hydrogen exchange: Studies in experimental cardiac fibrosis [J].
Young, M ;
Funder, J .
ENDOCRINOLOGY, 2003, 144 (09) :3848-3851