Synthesis of N-acylurea derivatives from carboxylic acids and N,N′-dialkyl carbodiimides in water

被引：26

作者：

Ramazani, Ali ^{[1
]}

Nasrabadi, Fatemeh Zeinali ^{[2
]}

Rezaei, Aram ^{[1
]}

Rouhani, Morteza ^{[3
]}

Ahankar, Hamideh ^{[4
]}

Asiabi, Pegah Azimzadeh ^{[1
]}

Joo, Sang Woo ^{[5
]}

Slepokura, Katarzyna ^{[6
]}

Lis, Tadeusz ^{[6
]}

机构：

[1] Univ Zanjan, Dept Chem, Zanjan, Iran

[2] Payame Noor Univ, Dept Chem, Tehran, Iran

[3] Islamic Azad Univ, Young Researchers & Elite Club, Zanjan Branch, Zanjan, Iran

[4] Islamic Azad Univ, Abhar Branch, Dept Chem, Abhar, Iran

[5] Yeungnam Univ, Sch Mech Engn, Kyongsan 712749, South Korea

[6] Univ Wroclaw, Fac Chem, PL-50383 Wroclaw, Poland

来源：

JOURNAL OF CHEMICAL SCIENCES | 2015年 / 127卷 / 12期

基金：

新加坡国家研究基金会;

关键词：

N; '-dialkylcarbodiimide; benzoic acid derivatives; (E)-cinnamic acid derivatives; O -> N acyl migration; N-acylurea; STABILIZED PHOSPHORUS YLIDES; SOLVENT-FREE CONDITIONS; ONE-POT SYNTHESIS; 1,3,4-OXADIAZOLE DERIVATIVES; 4-COMPONENT SYNTHESIS; 3-COMPONENT REACTION; STEREOSELECTIVE-SYNTHESIS; MULTICOMPONENT REACTIONS; (E)-CINNAMIC ACIDS; PEPTIDE SYNTHESIS;

D O I：

10.1007/s12039-015-0988-6

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Reactions of benzoic acid derivatives and (E)-cinnamic acid derivatives with -dialkyl carbodiimide proceed smoothly at room temperature and in neutral conditions to afford N-acylurea derivatives in high yields. The reaction proceeds smoothly and cleanly under mild conditions and no side reactions were observed.

引用

页码：2269 / 2282

页数：14

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