Dyspnoea: a multidimensional and multidisciplinary approach

被引:219
作者
Laviolette, Louis [1 ,2 ,5 ]
Laveneziana, Pierantonio [1 ,2 ,3 ,4 ]
机构
[1] Univ Sorbonne, UPMC Univ Paris 06, UMR S 1158, F-75005 Paris, France
[2] INSERM, UMR S 1158, F-75005 Paris, France
[3] Grp Hosp Pitie Salpetriere Charles Foix, AP HP, Serv Explorat Fonctionnelles Resp, F-75013 Paris, France
[4] Univ Paris Sud 11, Hop Univ Bicetre, AP HP,LabEx LERMIT Hypertens Arterielle Pulm, Ctr Reference Hypertens Pulm Severe,INSERM U999, Le Kremlin Bicetre, France
[5] CRIUCPQ, Quebec City, PQ, Canada
关键词
OBSTRUCTIVE PULMONARY-DISEASE; CHRONIC HEART-FAILURE; RESPIRATORY SOCIETY STATEMENT; AFFECTIVE DIMENSION; QUALITATIVE ASPECTS; EXERTIONAL DYSPNEA; AIR HUNGER; PSYCHOSOCIAL FACTORS; INHALED FUROSEMIDE; MENTAL-DISORDERS;
D O I
10.1183/09031936.00092613
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Dyspnoea is a debilitating symptom that affects quality of life, exercise tolerance and mortality in various disease conditions/states. In patients with chronic obstructive pulmonary disease (COPD), it has been shown to be a better predictor of mortality than forced expiratory volume in 1 s. In patients with heart disease it is a better predictor of mortality than angina. Dyspnoea is also associated with decreased functional status and worse psychological health in older individuals living at home. It also contributes to the low adherence to exercise training programmes in sedentary adults and in COPD patients. The mechanisms of dyspnoea are still unclear. Recent studies have emphasised the multidimensional nature of dyspnoea in the sensory-perceptual (intensity and quality), affective distress and impact domains. The perception of dyspnoea involves a complex chain of events that depend on varying cortical integration of several afferent/efferent signals and coloured by affective processing. This review, which stems from the European Respiratory Society research symposium held in Paris, France in November 2012, aims to provide state-of-the-art advances on the multidimensional and multidisciplinary aspects of dyspnoea, by addressing three different themes: 1) the neurophysiology of dyspnoea, 2) exercise and dyspnoea, and 3) the clinical impact and management of dyspnoea.
引用
收藏
页码:1750 / 1762
页数:13
相关论文
共 151 条
[1]   Prognostic significance of dyspnea in patients referred for cardiac stress testing [J].
Abidov, A ;
Rozanski, A ;
Hachamovitch, R ;
Hayes, SW ;
Aboul-Enein, F ;
Cohen, I ;
Friedman, JD ;
Germano, G ;
Berman, DS .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (18) :1889-1898
[2]  
[Anonymous], 1999, AM J RESP CRIT CARE, V159, pS1
[3]  
[Anonymous], COCHRANE DATABASE SY
[4]   AIR HUNGER ARISING FROM INCREASED P-CO2 IN MECHANICALLY VENTILATED QUADRIPLEGICS [J].
BANZETT, RB ;
LANSING, RW ;
REID, MB ;
ADAMS, L ;
BROWN, R .
RESPIRATION PHYSIOLOGY, 1989, 76 (01) :53-68
[5]   The affective dimension of laboratory dyspnea: Air hunger is more unpleasant than work/effort [J].
Banzett, Robert B. ;
Pedersen, Sarah H. ;
Schwartzstein, Richard M. ;
Lansing, Robert W. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2008, 177 (12) :1384-1390
[6]   Aerobic and strength training in patients with chronic obstructive pulmonary disease [J].
Bernard, S ;
Whittom, F ;
LeBlanc, P ;
Jobin, J ;
Belleau, R ;
Bérubé, C ;
Carrier, G ;
Maltais, F .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1999, 159 (03) :896-901
[7]   The Runner's High: Opioidergic Mechanisms in the Human Brain [J].
Boecker, Henning ;
Sprenger, Till ;
Spilker, Mary E. ;
Henriksen, Gjermund ;
Koppenhoefer, Marcus ;
Wagner, Klaus J. ;
Valet, Michael ;
Berthele, Achim ;
Tolle, Thomas R. .
CEREBRAL CORTEX, 2008, 18 (11) :2523-2531
[8]   An index for breathlessness and leg fatigue [J].
Borg, E. ;
Borg, G. ;
Larsson, K. ;
Letzter, M. ;
Sundblad, B. -M. .
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS, 2010, 20 (04) :644-650
[9]   The effectiveness of physiotherapy in patients with asthma: A systematic review of the literature [J].
Bruurs, Marjolein L. J. ;
van der Giessen, Lianne J. ;
Moed, Heleen .
RESPIRATORY MEDICINE, 2013, 107 (04) :483-494
[10]  
Cahalin LP, 2013, EXPERT REV CARDIOVAS, V11, P161, DOI [10.1586/ERC.12.191, 10.1586/erc.12.191]