Simple and convenient synthesis of fluoroalkenes via direct coupling of alcohols, alkynes and fluoroboric acid under metal-free conditions

被引：13

作者：

Yan, Xiao-wei ^{[1
,2
]}

Zhang, Qiang ^{[1
]}

Wei, Wei ^{[3
]}

Ji, Jian-xin ^{[1
]}

机构：

[1] Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China

[2] Univ Chinese Acad Sci, Beijing 100049, Peoples R China

[3] Qufu Normal Univ, Sch Chem & Chem Engn, Qufu 273165, Shandong, Peoples R China

来源：

TETRAHEDRON LETTERS | 2014年 / 55卷 / 28期

基金：

中国国家自然科学基金;

关键词：

Fluoroalkenes; Alkynes; Alcohols; Fluoroboric acid; Metal-free; ANTI-HIV ACTIVITY; STEREOSELECTIVE-SYNTHESIS; BOND FORMATION; EFFICIENT; FLUORINATION; HALIDES;

D O I：

10.1016/j.tetlet.2014.05.069

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and convenient method for the synthesis of fluoroalkenes from alkynes, alcohols and fluoroboric acid has been developed under mild conditions. The present protocol provides an attractive approach to access various fluoroalkenes from simple and commercially available starting materials without any metal catalyst, ligand or additive. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：3750 / 3752

页数：3

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