Laser Desorption Ionization Mass Spectrometry by Using Surface Plasmon Excitation on Gold Nanoparticle

被引：29
作者：
Shibamoto, K. [1 ]
Sakata, K. [1 ]
Nagoshi, K. [1 ]
Korenaga, T. [1 ]
机构：
[1] Tokyo Metropolitan Univ, Dept Chem, Tokyo 1920397, Japan
来源：
JOURNAL OF PHYSICAL CHEMISTRY C | 2009年 / 113卷 / 41期
关键词：
TIME-OF-FLIGHT; ULTRAFAST CHARGE-TRANSFER; FUNDAMENTAL PROCESSES; DESORPTION/IONIZATION; MATRIX; WAVELENGTH; SILICON;
D O I：
10.1021/jp9020432
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
We show development of a laser desorption/ionization (LDI) method with ultralligh sensitivity by adding gold nanoparticles with a diameter of several tens of nanometers into a sample solution. In this paper, we succeeded in detection of an ultratrace amount of sample molecules, which is less than several hundred zeptomoles. This result suggest that the charge interaction based on surface plasmon (SP) excitation is very effective for ultrahigh sensitivity in LDI method.
引用
收藏
页码：17774 / 17779
页数：6
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