Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes

被引：7

作者：

Yuki, Koichi ^{[1
,2
,3
]}

Hou, Lifei ^{[1
,2
,3
]}

Shibamura-Fujiogi, Miho ^{[1
,2
,3
]}

Koutsogiannaki, Sophia ^{[1
,2
,3
]}

Soriano, Sulpicio G. ^{[1
,2
]}

机构：

[1] Boston Childrens Hosp, Dept Anesthesiol Crit Care & Pain Med, Boston, MA 02115 USA

[2] Harvard Med Sch, Dept Anaesthesia, Boston, MA 02115 USA

[3] Harvard Med Sch, Dept Immunol, Boston, MA 02115 USA

来源：

CLINICAL IMMUNOLOGY | 2021年 / 222卷

关键词：

Volatile anesthetics; Immunomodulation; Surgery; NEUTROPHIL RECRUITMENT; LEUKOCYTE ADHESION; ACTIVATION; ISOFLURANE; SEVOFLURANE; RECEPTORS; SUBUNIT; MODULATION; INTEGRINS; BINDING;

D O I：

10.1016/j.clim.2020.108635

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A growing literature has shown that volatile anesthetics are promiscuous molecules targeting multiple molecules, some of which are critical for immunological functions. We focused on studies that delineated target molecules of volatile anesthetics on immune cells and summarized the effects of volatile anesthetics on immune functions. We also presented the perspectives of studying volatile anesthetics-mediated immunomodulation.

引用

页数：6

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