Hepcidin activation during inflammation: Make it STAT

被引:25
作者
Fleming, Robert E.
机构
[1] St Louis Univ, Sch Med, Dept Pediat, St Louis, MO 63104 USA
[2] St Louis Univ, Sch Med, Doisy Dept Biochem & Mol Biol, St Louis, MO 63104 USA
[3] Cardinal Glennon Childrens Hosp, Pediat Res Inst, St Louis, MO 63104 USA
关键词
D O I
10.1053/j.gastro.2006.11.049
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:447 / 449
页数:3
相关论文
共 14 条
[1]   Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression [J].
Babitt, JL ;
Huang, FW ;
Wrighting, DM ;
Xia, Y ;
Sidis, Y ;
Samad, TA ;
Campagna, JA ;
Chung, RT ;
Schneyer, AL ;
Woolf, CJ ;
Andrews, NC ;
Lin, HY .
NATURE GENETICS, 2006, 38 (05) :531-539
[2]   C/EBPα regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism [J].
Courselaud, B ;
Pigeon, C ;
Inoue, Y ;
Inoue, J ;
Gonzalez, FJ ;
Leroyer, P ;
Gilot, D ;
Boudjema, K ;
Guguen-Guillouzo, C ;
Brissott, P ;
Loréal, O ;
Ilyin, G .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (43) :41163-41170
[3]  
FALZACAPPA MVV, 2006, BLOOD 0831
[4]  
Ganz T, 2006, CURR TOP MICROBIOL, V306, P183
[5]   Principles of interleukin (IL)-6-type cytokine signalling and its regulation [J].
Heinrich, PC ;
Behrmann, I ;
Haan, S ;
Hermanns, HM ;
Müller-Newen, G ;
Schaper, F .
BIOCHEMICAL JOURNAL, 2003, 374 (01) :1-20
[6]   Upregulation of hepcidin by interleukin-1β in human hepatoma cell lines [J].
Inamura, J ;
Ikuta, K ;
Jimbo, J ;
Shindo, M ;
Sato, K ;
Torimoto, Y ;
Kohgo, Y .
HEPATOLOGY RESEARCH, 2005, 33 (03) :198-205
[7]   Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-β signaling [J].
Jenkins, BJ ;
Grail, D ;
Nheu, T ;
Najdovska, M ;
Wang, B ;
Waring, P ;
Inglese, M ;
McLoughlin, RM ;
Jones, SA ;
Topley, N ;
Baumann, H ;
Judd, LM ;
Giraud, AS ;
Boussioutas, A ;
Zhu, HJ ;
Ernst, M .
NATURE MEDICINE, 2005, 11 (08) :845-852
[8]   Regulation of hepcidin transcription by interleukin-1 and interleukin-6 [J].
Lee, P ;
Peng, HF ;
Gelbart, T ;
Wang, L ;
Beutler, E .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (06) :1906-1910
[9]   Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3) [J].
Long, JY ;
Wang, GN ;
Matsuura, I ;
He, DM ;
Liu, F .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (01) :99-104
[10]   STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo [J].
Pietrangelo, Antonello ;
Dierssen, Uta ;
Valli, Linda ;
Garuti, Cinzia ;
Rump, Agrani ;
Corradini, Elena ;
Ernst, Matthias ;
Klein, Christian ;
Trautwein, Christian .
GASTROENTEROLOGY, 2007, 132 (01) :294-300