Epstein-Barr Virus-associated Smooth Muscle Tumors in AIDS Patients: A Largest Case (Series)

被引：20
|
作者：
Issarachaikul, Ratima [1 ]
Shuangshoti, Shanop [2 ]
Suankratay, Chusana [1 ]
机构：
[1] Chulalongkorn Univ, Dept Med, Div Infect Dis, Bangkok 10330, Thailand
[2] Chulalongkorn Univ, Fac Med, Dept Pathol, Bangkok 10330, Thailand
来源：
INTERNAL MEDICINE | 2014年 / 53卷 / 20期
关键词：
Epstein-Barr virus; smooth muscle tumors; AIDS; HIV; ACQUIRED-IMMUNODEFICIENCY-SYNDROME; NASOPHARYNGEAL; LEIOMYOSARCOMA; MALIGNANCIES; DNA;
D O I：
10.2169/internalmedicine.53.2674
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This study aimed to determine the outcomes of Epstein-Barr virus (EBV)-associated smooth muscle tumors (SMTs) in AIDS patients at King Chulalongkorn Memorial Hospital, Bangkok, Thailand, treated from 2001-2011. Of the 17 patients, there were five men with a median CD4 count of 26 cells/mu L. Eight and nine patients had single and multiple sites, respectively. The most common site was the cranial epidura (58.8%). All patients had EBV within the tumor. Seven patients underwent surgery. The median follow-up was one year. The mortality rate was 41.2%. All patients with undetectable HIV viremia survived. This is the largest case series regarding EBV-associated SMTs in AIDS patients with a long follow-up period.
引用
收藏
页码：2391 / 2396
页数：6
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