Evaluation of the oxygenation index in adult respiratory failure

被引：45

作者：

Dechert, Ronald E. ^{[1
]}

Park, Pauline K. ^{[1
]}

Bartlett, Robert H. ^{[1
]}

机构：

[1] Univ Michigan, Dept Surg, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF TRAUMA AND ACUTE CARE SURGERY | 2014年 / 76卷 / 02期

关键词：

ARDS; scoring systems; mortality risk; risk assessment; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE LUNG INJURY; INHALED NITRIC-OXIDE; DISTRESS-SYNDROME; HOSPITAL MORTALITY; TERM; PREDICTORS; SURVIVAL; NEWBORNS; DEATH;

D O I：

10.1097/TA.0b013e3182ab0d27

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

BACKGROUND: The oxygenation index (mean airway pressure x FIO2 divided by PaO2) was originally devised to measure severity of illness and predict outcome in neonatal respiratory failure. We evaluated the discrimination of a modified oxygenation index (modified with age) for predicting 28-day mortality in adults with respiratory failure (adult respiratory distress syndrome [ARDS]) using the ALVEOLI section of the ARDSNet database and validated the results in the full ARDSNet database. METHODS: We compared age-adjusted oxygenation index (AOI) on ventilator Days 1 to 4 with 28-day mortality. RESULTS: AOI correlated positively with mortality (area under the receiver operating characteristic curve, 0.70-0.74, for ARDS Days 1-4). Following initial development, AOI related to mortality was validated in two other ARDSNet databases producing similar results (area under the receiver operating characteristic curve, 0.70-0.78). CONCLUSION: The observed sensitivity and specificity analysis demonstrated that AOI is equivalent to or better than other mortality prediction systems used for ARDS. Copyright (C) 2014 by Lippincott Williams & Wilkins

引用

页码：469 / 473

页数：5

共 36 条

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