Chemical sensing with nanoparticles as optical reporters: from noble metal nanoparticles to quantum dots and upconverting nanoparticles

被引：40

作者：

Deng, Wei ^{[1
]}

Goldys, Ewa M. ^{[1
]}

机构：

[1] Macquarie Univ, Ctr Nanoscale BioPhoton, N Ryde, NSW 2109, Australia

来源：

ANALYST | 2014年 / 139卷 / 21期

基金：

澳大利亚研究理事会;

关键词：

SURFACE-PLASMON RESONANCE; PROXIMITY LIGATION ASSAY; MODIFIED MESOPOROUS SILICA; ENERGY-TRANSFER; GOLD NANOPARTICLES; ENHANCED FLUORESCENCE; SILVER NANOPARTICLES; RAMAN-SPECTROSCOPY; MOLECULAR BEACONS; COLORIMETRIC DETECTION;

D O I：

10.1039/c4an01272k

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A wide variety of biological and medical analyses are based on the use of optical signals to report specific molecular events. Thanks to advances in nanotechnology, various nanostructures have been extensively used as optical reporters in bio- and chemical assays. This review describes recent progress in chemical sensing using noble metal nanoparticles (gold and silver), quantum dots and upconverting nanoparticles. It provides insights into various nanoparticle-based sensing strategies including fluorescence/luminescence resonance energy transfer nanoprobes as well as activatable probes sensitive to specific changes in the biological environment. Finally we list some research challenges to be overcome in order to accelerate the development of applications of nanoparticle bio- and chemical sensors.

引用

页码：5321 / 5334

页数：14

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