New syntheses of 5,6-and 7,8-diaminoquinolines

被引：6

作者：

Bella, Maros ^{[1
]}

Milata, Viktor ^{[2
]}

机构：

[1] Slovak Acad Sci, Inst Chem, SK-84538 Bratislava, Slovakia

[2] Slovak Univ Technol Bratislava, Fac Chem & Food Technol, Dept Organ Chem, SK-81237 Bratislava, Slovakia

来源：

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷

关键词：

chlorination; deselenation; nitrogen heterocycles; o-diaminoquinolines; selenadiazoloquinolones; DERIVATIVES;

D O I：

10.3762/bjoc.9.302

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 5,6- and 7,8-diaminoquinoline derivatives starting from angularly annelated selenadiazoloquinolones is presented. Simple chlorination of the pyridone ring followed by reductive deselenation of the 1,2,5-selenadiazole ring afforded novel 4-chloro-o-diaminoquinolines. Dechlorination of 4-chloro-7,8-diaminoquinoline gave 7,8-diaminoquinoline hydrochloride which was successfully employed as starting material in the synthesis of condensed nitrogen heterocycles.

引用

页码：2669 / 2674

页数：6

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