Comparative Pathology of the Peripheral Nervous System

被引:29
作者
Lanigan, Lisa G. [1 ]
Russell, Duncan S. [2 ]
Woolard, Kevin D. [3 ]
Pardo, Ingrid D. [4 ]
Godfrey, Virginia [5 ]
Jortner, Bernard S. [6 ]
Butt, Mark T. [1 ]
Bolon, Brad [7 ]
机构
[1] StageBio Inc, 8420 Gas House Pike,Suite G, Frederick, MD 21701 USA
[2] Oregon State Univ, Corvallis, OR 97331 USA
[3] Univ Calif Davis, Davis, CA 95616 USA
[4] Pfizer Inc, Groton, CT 06340 USA
[5] Univ N Carolina, Chapel Hill, NC 27515 USA
[6] Virginia Tech, Blacksburg, VA USA
[7] GEMpath Inc, Longmont, CO USA
关键词
neuropathy; ganglia; nerve; neuritis; nerve sheath tumor; neuropathology; autonomic nervous system; neurotoxicity; SHEATH TUMORS; ANIMAL-MODELS; CAUDA-EQUINA; NEUROLOGICAL MANIFESTATIONS; DIAGNOSTIC-CRITERIA; PARATHYROID-HORMONE; VIRUS-INFECTIONS; MEDICAL PROGRESS; BARRIER FUNCTION; BRACHIAL-PLEXUS;
D O I
10.1177/0300985820959231
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The peripheral nervous system (PNS) relays messages between the central nervous system (brain and spinal cord) and the body. Despite this critical role and widespread distribution, the PNS is often overlooked when investigating disease in diagnostic and experimental pathology. This review highlights key features of neuroanatomy and physiology of the somatic and autonomic PNS, and appropriate PNS sampling and processing techniques. The review considers major classes of PNS lesions including neuronopathy, axonopathy, and myelinopathy, and major categories of PNS disease including toxic, metabolic, and paraneoplastic neuropathies; infectious and inflammatory diseases; and neoplasms. This review describes a broad range of common PNS lesions and their diagnostic criteria and provides many useful references for pathologists who perform PNS evaluations as a regular or occasional task in their comparative pathology practice.
引用
收藏
页码:10 / 33
页数:24
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