Surface functional DNA density control by programmable molecular defects

被引：12

作者：

Chen, Chong-You ^{[1
]}

Wang, Chang-Ming ^{[1
]}

Chen, Pai-Shan ^{[2
]}

Liao, Wei-Ssu ^{[1
]}

机构：

[1] Natl Taiwan Univ, Dept Chem, Taipei 10617, Taiwan

[2] Natl Taiwan Univ, Dept & Grad Inst Forens Med, Taipei 10002, Taiwan

来源：

CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 33期

关键词：

SELF-ASSEMBLED MONOLAYERS; DIP-PEN NANOLITHOGRAPHY; SINGLE-STRANDED-DNA; DIRECTED IMMOBILIZATION; GOLD; PROBE; OLIGONUCLEOTIDE; LITHOGRAPHY; ADSORPTION; INTERFACE;

D O I：

10.1039/c7cc09908h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.

引用

收藏

页码：4100 / 4103

页数：4

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