Compound dual radiation action theory for 252CF brachytherapy

被引：3

作者：

Wang, CK ^{[1
]}

Zhang, X ^{[1
]}

机构：

[1] Georgia Inst Technol, Nucl & Radiol Engn Program, Neely Res Ctr, Atlanta, GA 30332 USA

来源：

RADIATION PROTECTION DOSIMETRY | 2004年 / 110卷 / 1-4期

关键词：

D O I：

10.1093/rpd/nch165

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

The existing dosimetry protocol that uses the concept of RBE for Cf-252 brachytherapy contains large uncertainties. A new formula has been developed to correlate the biological effect (i.e. cell survival fraction) resulting from a mixed n + gamma radiation field with two physical quantities and two biological quantities. The formula is based on a pathway model evolved from that of the compound-dual-radiation-action (CDRA) theory, previously proposed by Rossi and Zaider. The new model employs the recently published data on radiation-induced DNA lesions. The new formula is capable of predicting quantitatively the synergistic effect caused by the interactions between neutron events and gamma ray events, and it is intended to be included into a new dosimetry protocol for future Cf-252 brachytherapy.

引用

页码：801 / 806

页数：6

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