Statistical and conceptual issues in defining post-operative cognitive dysfunction

被引：55
作者：
Lewis, M
Maruff, P
Silbert, B
机构：
[1] St Vincents Hosp, Ctr Anaesthesia & Cognit Funct, Dept Anesthesia, Melbourne, Vic 3065, Australia
[2] La Trobe Univ, Sch Psychol Sci, Melbourne, Vic 3086, Australia
来源：
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2004年 / 28卷 / 04期
基金：
英国医学研究理事会;
关键词：
POCD; post-operative cognitive dysfunction; surgery; statistics; change; ageing;
D O I：
10.1016/j.neubiorev.2004.05.002
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The occurrence of post-operative cognitive dysfunction is a distressing complication following surgery. In an effort to gain a more complete understanding of patients' cognitive recovery following surgical procedures common neuropsychological assessment tools have been adopted in a repeated measures design. It is widely regarded that this represents the most comprehensive method of determining cognitive status in this population but it has resulted in a number of statistical and conceptual difficulties in attempting to infer significant change. The current paper outlines these core difficulties and provides some potential methods to overcome these. (C) 2004 Elsevier Ltd. All rights reserved.
引用
收藏
页码：433 / 440
页数：8
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