Dextran-induced pulmonary edema in patients with sudden deafness

被引:14
作者
Kuo, ST [1 ]
Hsu, WC [1 ]
Young, YH [1 ]
机构
[1] Natl Taiwan Univ Hosp, Dept Otolaryngol, Taipei, Taiwan
关键词
sudden deafness; dextran; pulmonary edema; fever; oliguria;
D O I
10.1097/00129492-200209000-00010
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objective: Pulmonary complication in cases of sudden deafness after dextran treatment is rarely reported. This study discusses the management of two cases and reviews the current literature. Patients: Two (1%) of 204 patients with sudden deafness patients had fever, cough, and dyspnea after intravenous dextran infusion. Pulmonary edema was diagnosed after chest radiographic examination. Results: After interruption of dextran, subsequent supportive treatment relieved chest discomfort and fever without any sequelae. The results of chest radiograph and laboratory studies, including hemogram, renal function, and arterial blood oxygen saturation, were normal. Conclusions: Patients receiving dextran treatment should have their clinical symptoms, renal function, chest radiographs, hemogram, and coagulation profiles monitored. If fever, bleeding, cough, or dyspnea occurs during treatment, dextran must be immediately stopped. Subsequent treatment should focus on dextran clearance to prevent further cascade complications.
引用
收藏
页码:661 / 664
页数:4
相关论文
共 24 条
[1]   Sudden sensorineural hearing loss -: Does application of glucocorticoids make sense? [J].
Alexiou, C ;
Arnold, W ;
Fauser, C ;
Schratzenstaller, B ;
Gloddek, B ;
Fuhrmann, S ;
Lamm, K .
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2001, 127 (03) :253-258
[2]   PATHOLOGY OF VASCULAR SENSORINEURAL HEARING IMPAIRMENT [J].
BELAL, A .
LARYNGOSCOPE, 1980, 90 (11) :1831-1839
[3]   Incidence of acute oligoanuric renal failure in dextran 40 treated patients with acute ischemic stroke stage III or IV [J].
Biesenbach, G ;
Kaiser, W ;
Zazgornik, J .
RENAL FAILURE, 1997, 19 (01) :69-75
[4]  
DRUML W, 1988, NEW ENGL J MED, V318, P252
[5]   Dextran syndrome - Acute hypotension, noncardiogenic pulmonary edema, anemia, and coagulopathy following hysteroscopic surgery using 32% dextran 70 [J].
Ellingson, TL ;
Aboulafia, DM .
CHEST, 1997, 111 (02) :513-514
[6]  
Gossman DE, 1996, CATHETER CARDIO DIAG, V38, P56
[7]   DECREASE IN HEMATOCRIT ALTER CORONARY STENT PLACEMENT AND DEXTRAN THERAPY [J].
HAUGHT, WH ;
SOKOL, M ;
KERENSKY, RA ;
MEHTA, JL .
AMERICAN JOURNAL OF CARDIOLOGY, 1995, 76 (04) :314-315
[8]  
Hughes GB, 1996, OTOLARYNG CLIN N AM, V29, P393
[9]   SUDDEN DEAFNESS - A RETROSPECTIVE EVALUATION OF DEXTRAN THERAPY [J].
HULTCRANTZ, E ;
STENQUIST, M ;
LYTTKENS, L .
ORL-JOURNAL FOR OTO-RHINO-LARYNGOLOGY AND ITS RELATED SPECIALTIES, 1994, 56 (03) :137-142