International Consensus Recommendations for Eosinophilic Gastrointestinal Disease Nomenclature

被引：104

作者：

Dellon, Evan S. ^{[1
,2
]}

Gonsalves, Nirmala ^{[3
]}

Abonia, J. Pablo ^{[4
]}

Alexander, Jeffrey A. ^{[5
]}

Arva, Nicoleta C. ^{[6
]}

Atkins, Dan ^{[7
]}

Attwood, Stephen E. ^{[8
]}

Auth, Marcus K. H. ^{[9
,10
]}

Bailey, Dominique D. ^{[11
,12
,13
]}

Biederman, Luc ^{[14
]}

Blanchard, Carine ^{[15
]}

Bonis, Peter A. ^{[16
]}

Bose, Paroma ^{[17
]}

Bredenoord, Albert J. ^{[18
]}

Chang, Joy W. ^{[19
]}

Chehade, Mirna ^{[20
]}

Collins, Margaret H. ^{[21
]}

Di Lorenzo, Carlo ^{[22
]}

Dias, Jorge Amil ^{[23
]}

Dohil, Ranjan ^{[24
]}

Dupont, Christophe ^{[25
]}

Falk, Gary W. ^{[26
]}

Ferreira, Cristina T. ^{[27
]}

Fox, Adam T. ^{[28
]}

Genta, Robert M. ^{[29
,30
]}

Greuter, Thomas ^{[14
,31
]}

Gupta, Sandeep K. ^{[17
]}

Hirano, Ikuo ^{[3
]}

Hiremath, Girish S. ^{[32
]}

Horsley-Silva, Jennifer L. ^{[33
]}

Ishihara, Shunji ^{[34
]}

Ishimura, Norihisa ^{[34
]}

Jensen, Elizabeth T. ^{[35
]}

Gutierrez-Junquera, Carolina ^{[36
]}

Katzka, David A. ^{[5
]}

Khoury, Paneez ^{[37
]}

Kinoshita, Yoshikazu ^{[38
]}

Kliewer, Kara L. ^{[4
]}

Koletzko, Sibylle ^{[39
,40
]}

Leung, John ^{[16
]}

Liacouras, Chris A. ^{[41
]}

Lucendo, Alfredo J. ^{[42
]}

Martin, Lisa J. ^{[43
]}

McGowan, Emily C. ^{[44
]}

Menard-Katcher, Calies ^{[45
,46
]}

Metz, David C. ^{[26
]}

Miller, Talya L. ^{[47
]}

Moawad, Fouad J. ^{[48
]}

Muir, Amanda B. ^{[41
]}

Mukkada, Vincent A. ^{[49
]}

机构：

[1] Univ N Carolina, Ctr Esophageal Dis & Swallowing, Sch Med, Chapel Hill, NC 27515 USA

[2] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Dept Med, Div Gastroenterol & Hepatol,Sch Med, Chapel Hill, NC 27515 USA

[3] Northwestern Univ, Feinberg Sch Med, Div Gastroenterol & Hepatol, Chicago, IL 60611 USA

[4] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati Childrens Hosp Med Ctr,Div Allergy & I, Cincinnati, OH USA

[5] Mayo Clin Rochester, Div Gastroenterol, Rochester, MN USA

[6] Northwestern Univ, Dept Pathol, Ann & Robert H Lurie Childrens Hosp Chicago, Feinberg Sch Med, Chicago, IL 60611 USA

[7] Univ Colorado, Childrens Hosp Colorado, Sch Med, Sect Pediat Allergy & Immunol, Aurora, CO USA

[8] Univ Durham, Dept Hlth Serv Res, Durham, England

[9] Alder Hey Childrens NHS Fdn Trust, Dept Paediat Gastroenterol Hepatol & Nutr, Liverpool, Merseyside, England

[10] Univ Liverpool, Liverpool, Merseyside, England

[11] Columbia Univ, Dept Pediat, Irving Med Ctr, Div Pediat Gastroenterol Hepatol & Nutr, New York, NY 10027 USA

[12] Columbia Univ, Dept Med, Irving Med Ctr, Div Digest & Liver Dis, New York, NY USA

[13] Columbia Univ, Columbia Ctr Human Dev, Irving Med Ctr, New York, NY USA

[14] Univ Hosp Zurich, Dept Gastroenterol & Hepatol, Zurich, Switzerland

[15] Soc Prod Nestle SA, Nestle Inst Hlth Sci, Nestle Res, Dept Gastrointestinal Hlth,Immunol Grp, Lausanne, Switzerland

[16] Tufts Univ, Sch Med, Div Gastroenterol, Boston, MA 02111 USA

[17] Indiana Univ Sch Med, Riley Hosp Children & Community Hlth Network, Div Pediat Gastroenterol Hepatol & Nutr, Indianapolis, IN 46202 USA

[18] Univ Amsterdam, Dept Gastroenterol, Med Ctr, Amsterdam, Netherlands

[19] Univ Michigan, Dept Internal Med, Div Gastroenterol, Ann Arbor, MI 48109 USA

[20] Icahn Sch Med Mt Sinai, Mt Sinai Ctr Eosinophil Disorders, New York, NY 10029 USA

[21] Univ Cincinnati, Dept Pediat, Cincinnati Childrens Hosp Med Ctr, Div Pathol & Lab Med,Coll Med, Cincinnati, OH USA

[22] Nationwide Childrens Hosp, Div Gastroenterol Hepatol & Nutr, Columbus, OH USA

[23] Hosp Lusiadas, Porto, Portugal

[24] Univ Calif San Diego, Radys Childrens Hosp, Div Pediat Gastroenterol, San Diego, CA 92103 USA

[25] Paris Descartes Univ, Marcel Sembat Clin, Ramsay Grp, Paris, France

[26] Univ Penn, Perelman Sch Med, Div Gastroenterol, Philadelphia, PA 19104 USA

[27] Fed Univ Hlth Sci Porto Alegre, Hosp Santo Antonio, Porto Alegre, RS, Brazil

[28] Guys & St Thomas Hosp NHS Fdn Trust, Paediat Allergy, London, England

[29] Baylor Coll Med, Div Gastroenterol, Dept Pathol & Med, Houston, TX 77030 USA

[30] Inform Diagnost, Irving, TX USA

[31] Univ Hosp Lausanne, Div Gastroenterol & Hepatol, Lausanne, Switzerland

[32] Vanderbilt Univ, Monroe Carell Jr Childrens Hosp Vanderbilt, Div Pediat Gastroenterol Hepatol & Nutr, Med Ctr, Nashville, TN USA

[33] Mayo Clin, Div Gastroenterol & Hepatol, Phoenix, AZ USA

[34] Shimane Univ, Fac Med, Dept Internal Med 2, Matsue, Shimane, Japan

[35] Wake Forest Sch Med, Dept Epidemiol & Prevent, Winston Salem, NC 27101 USA

[36] Autonomous Univ Madrid, Univ Hosp Puerta de Hierro Majadahonda, Pediat Gastroenterol Unit, Majadahonda, Spain

[37] NIAID, Human Eosinophil Sect, NIH, 9000 Rockville Pike, Bethesda, MD 20892 USA

[38] Hyogo Prefectural Harima Himeji Gen Med Ctr, Himeji, Hyogo, Japan

[39] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Pediat, Dr von Hauner Childrens Hosp, Munich, Germany

[40] Univ Warmia & Mazury, Coll Med, Sch Med, Dept Pediat Gastroenterol & Nutr, Olsztyn, Poland

[41] Univ Penn, Childrens Hosp Philadelphia, Perelman Sch Med, Ctr Pediat Eosinophil Disorders,Div Gastroenterol, Philadelphia, PA 19104 USA

[42] Hosp Gen Tomelloso, Ctr Invest Biomed Red Enfermedades Hepat & Digest, Inst Invest Sanitaria Princesa, Dept Gastroenterol, Tomelloso, Spain

[43] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati Childrens Hosp, Cincinnati, OH USA

[44] Univ Virginia, Sch Med, Div Allergy & Immunol, Charlottesville, VA 22908 USA

[45] Childrens Hosp Colorado, Digest Hlth Inst, Aurora, CO USA

[46] Univ Colorado, Sch Med, Gastrointestinal Eosinophil Dis Program, Aurora, CO USA

[47] Swedish Med Ctr, Seattle, WA USA

[48] Scripps Clin, Div Gastroenterol & Hepatol, La Jolla, CA USA

[49] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati Childrens Hosp Med Ctr,Div Gastroenter, Cincinnati, OH USA

[50] Univ Warwick, Med Sch, Coventry, W Midlands, England

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2022年 / 20卷 / 11期

关键词：

Eosinophilic Gastrointestinal Disease; Eosinophilic Gastroenteritis; Delphi; Nomenclature; Classification; GASTRITIS AND/OR DUODENITIS; JOINT TASK-FORCE; AGA INSTITUTE; GASTROENTERITIS; ESOPHAGITIS; MANAGEMENT; DISORDERS; CHILDREN;

D O I：

10.1016/j.cgh.2022.02.017

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

BACKGROUND & AIMS: Substantial heterogeneity in terminology used for eosinophilic gastrointestinal diseases (EGIDs), particularly the catchall term "eosinophilic gastroenteritis," limits clinical and research advances. We aimed to achieve an international consensus for standardized EGID nomenclature. METHODS: This consensus process utilized Delphi methodology. An initial naming framework was proposed and refined in iterative fashion, then assessed in a first round of Delphi voting. Results were discussed in 2 consensus meetings, and the framework was updated and reassessed in a second Delphi vote, with a 70% threshold set for agreement. RESULTS: Of 91 experts participating, 85 (93%) completed the first and 82 (90%) completed the second Delphi surveys. Consensus was reached on all but 2 statements. "EGID" was the preferred umbrella term for disorders of gastrointestinal (GI) tract eosinophilic inflammation in the absence of secondary causes (100% agreement). Involved GI tract segments will be named specifically and use an "Eo" abbreviation convention: eosinophilic gastritis (now abbreviated EoG), eosinophilic enteritis (EoN), and eosinophilic colitis (EoC). The term "eosinophilic gastroenteritis" is no longer preferred as the overall name (96% agreement). When >2 GI tract areas are involved, the name should reflect all of the involved areas. CONCLUSIONS: This international process resulted in consensus for updated EGID nomenclature for both clinical and research use. EGID will be the umbrella term, rather than "eosinophilic gastroenteritis," and specific naming conventions by location of GI tract involvement are recommended. As more data are developed, this framework can be updated to reflect best practices and the underlying science.

引用

页码：2474 / +

页数：14

共 31 条

[1] Histologic eosinophilic gastritis is a systemic disorder associated with blood and extragastric eosinophilia, TH2 immunity, and a unique gastric transcriptome [J].

Caldwell, Julie M. ;

Collins, Margaret H. ;

Stucke, Emily M. ;

Putnam, Philip E. ;

Franciosi, James P. ;

Kushner, Jonathan P. ;

Abonia, J. Pablo ;

Rothenberg, Marc E. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (05) :1114-1124

[2] A Shift in the Clinical Spectrum of Eosinophilic Gastroenteritis Toward the Mucosal Disease Type [J].

Chang, Joseph Y. ;

Choung, Rok Seon ;

Lee, Ru Min ;

Locke, G. Richard, III ;

Schleck, Cathy D. ;

Zinsmeister, Alan R. ;

Smyrk, Thomas C. ;

Talley, Nicholas J. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2010, 8 (08) :669-675

[3] Diagnostic Delay in Patients with Eosinophilic Gastritis and/or Duodenitis: A Population-Based Study [J].

Chehade, Mirna ;

Kamboj, Amol P. ;

Atkins, Dan ;

Gehman, Lauren T. .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2021, 9 (05) :2050-+

[4] Variability in diagnostic criteria for eosinophilic esophagitis: A systematic review [J].

Dellon, Evan S. ;

Aderoju, Ademola ;

Woosley, John T. ;

Sandler, Robert S. ;

Shaheen, Nicholas J. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2007, 102 (10) :2300-2313

[5] Determination of Biopsy Yield That Optimally Detects Eosinophilic Gastritis and/or Duodenitis in a Randomized Trial of Lirentelimab [J].

Dellon, Evan S. ;

Gonsalves, Nirmala ;

Rothenberg, Marc E. ;

Hirano, Ikuo ;

Chehade, Mirna ;

Peterson, Kathryn A. ;

Falk, Gary W. ;

Murray, Joseph A. ;

Gehman, Lauren T. ;

Chang, Alan T. ;

Singh, Bhupinder ;

Rasmussen, Henrik S. ;

Genta, Robert M. .

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2022, 20 (03) :535-+

[6] Anti-Siglec-8 Antibody for Eosinophilic Gastritis and Duodenitis [J].

Dellon, Evan S. ;

Peterson, Kathryn A. ;

Murray, Joseph A. ;

Falk, Gary W. ;

Gonsalves, Nirmala ;

Chehade, Mirna ;

Genta, Robert M. ;

Leung, John ;

Khoury, Paneez ;

Klion, Amy D. ;

Hazan, Sabine ;

Vaezi, Michael ;

Bledsoe, Adam C. ;

Durrani, Sandy R. ;

Wang, Chao ;

Shaw, Camilla ;

Chang, Alan T. ;

Singh, Bhupinder ;

Kamboj, Amol P. ;

Rasmussen, Henrik S. ;

Rothenberg, Marc E. ;

Hirano, Ikuo .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (17) :1624-1634

[7] Substantial Variability in Biopsy Practice Patterns Among Gastroenterologists for Suspected Eosinophilic Gastrointestinal Disorders [J].

Dellon, Evan S. ;

Collins, Margaret H. ;

Bonis, Peter A. ;

Leung, John ;

Capocelli, Kelley E. ;

Dohil, Ranjan ;

Falk, Gary W. ;

Furuta, Glenn T. ;

Menard-Katcher, Calies ;

Gupta, Sandeep K. ;

Hirano, Ikuo ;

Hiremath, Girish S. ;

Kagalwalla, Amir F. ;

Wershil, Barry K. ;

Liacouras, Chris A. ;

Muir, Amanda B. ;

Mukkada, Vincent A. ;

Putnam, Philip E. ;

Schoepfer, Alain M. ;

Straumann, Alex ;

Wo, John M. ;

Yang, Guang-Yu ;

Rothenberg, Marc E. ;

Gonsalves, Nirmala .

Clinical Gastroenterology and Hepatology, 2016, 14 (12) :1842-1844

[8]

Gonsalves N, 2020, GASTROENTEROLOGY, V158, pS43

[9] Eosinophilic Gastrointestinal Disorders [J].

Gonsalves, Nirmala .

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY, 2019, 57 (02) :272-285

[10] Eosinophilic Gastroenteritis: Clinical Manifestation, Natural Course, and Evaluation of Treatment with Corticosteroids and Vedolizumab [J].

Grandinetti, Tanja ;

Biedermann, Luc ;

Bussmann, Christian ;

Straumann, Alex ;

Hruz, Petr .

DIGESTIVE DISEASES AND SCIENCES, 2019, 64 (08) :2231-2241

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