CD44 and xCT: The Silver Bullet for Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension?

被引：4
作者：
Agrawal, Vineet [1 ]
Hemnes, Anna R. [1 ]
机构：
[1] Vanderbilt Univ, Med Ctr, Dept Med, Nashville, TN 37212 USA
来源：
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | 2019年 / 61卷 / 03期
关键词：
D O I：
10.1165/rcmb.2019-0135ED
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：281 / 283
页数：3
相关论文
共 21 条
[1]   Echocardiographic evaluation of diastolic function in the setting of pulmonary hypertension [J].
Agrawal, Vineet ;
Byrd, Benjamin F., III ;
Brittain, Evan L. .
PULMONARY CIRCULATION, 2019, 9 (01)
[2]   Clinical and Biological Insights Into Combined Post- and Pre-Capillary Pulmonary Hypertension [J].
Assad, Tufik R. ;
Hemnes, Anna R. ;
Larkin, Emma K. ;
Glazer, Andrew M. ;
Xu, Meng ;
Wells, Quinn S. ;
Farber-Eger, Eric H. ;
Sheng, Quanhu ;
Shyr, Yu ;
Harrell, Frank E. ;
Newman, John H. ;
Brittain, Evan L. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2016, 68 (23) :2525-2536
[3]   Metabolic Dysfunction in Pulmonary Arterial Hypertension [J].
Assad, Tufik R. ;
Hemnes, Anna R. .
CURRENT HYPERTENSION REPORTS, 2015, 17 (04)
[4]   The cancer theory of pulmonary arterial hypertension [J].
Boucherat, Olivier ;
Vitry, Geraldine ;
Trinh, Isabelle ;
Paulin, Roxane ;
Provencher, Steeve ;
Bonnet, Sebastien .
PULMONARY CIRCULATION, 2017, 7 (02) :285-299
[5]   Fatty Acid Metabolic Defects and Right Ventricular Lipotoxicity in Human Pulmonary Arterial Hypertension [J].
Brittain, Evan L. ;
Talati, Megha ;
Fessel, Joshua P. ;
Zhu, He ;
Penner, Niki ;
Calcutt, M. Wade ;
West, James D. ;
Funke, Mitch ;
Lewis, Gregory D. ;
Gerszten, Robert E. ;
Hamid, Rizwan ;
Pugh, Meredith E. ;
Austin, Eric D. ;
Newman, John H. ;
Hemnes, Anna R. .
CIRCULATION, 2016, 133 (20) :1936-1944
[6]   Oestrogen inhibition reverses pulmonary arterial hypertension and associated metabolic defects [J].
Chen, Xinping ;
Austin, Eric D. ;
Talati, Megha ;
Fessel, Joshua P. ;
Farber-Eger, Eric H. ;
Brittain, Evan L. ;
Hemnes, Anna R. ;
Loyd, James E. ;
West, James .
EUROPEAN RESPIRATORY JOURNAL, 2017, 50 (02)
[7]   Endothelial to mesenchymal transition in the cardiovascular system [J].
Gong, Hui ;
Lyu, Xing ;
Wang, Qiong ;
Hu, Min ;
Zhang, Xiangyu .
LIFE SCIENCES, 2017, 184 :95-102
[8]  
GREENFIELD SM, 1993, ALIMENT PHARM THER, V7, P369
[9]   Human PAH is characterized by a pattern of lipid-related insulin resistance [J].
Hemnes, Anna R. ;
Luther, J. Matthew ;
Rhodes, Christopher J. ;
Burgess, Jason P. ;
Carlson, James ;
Fan, Run ;
Fessel, Joshua P. ;
Fortune, Niki ;
Gerszten, Robert E. ;
Halliday, Stephen J. ;
Hekmat, Rezzan ;
Howard, Luke ;
Newman, John H. ;
Niswender, Kevin D. ;
Pugh, Meredith E. ;
Robbins, Ivan M. ;
Sheng, Quanhu ;
Shibao, Cyndya A. ;
Shyr, Yu ;
Sumner, Susan ;
Talati, Megha ;
Wharton, John ;
Wilkins, Martin R. ;
Ye, Fei ;
Yu, Chang ;
West, James ;
Brittain, Evan L. .
JCI INSIGHT, 2019, 4 (01)
[10]   Pathobiology of pulmonary arterial hypertension: understanding the roads less travelled [J].
Hemnes, Anna R. ;
Humbert, Marc .
EUROPEAN RESPIRATORY REVIEW, 2017, 26 (146)
123