Laryngeal hypersensitivity in chronic cough

被引：28

作者：

Hull, J. H. ^{[1
]}

Menon, A. ^{[1
]}

机构：

[1] Royal Brompton Hosp, Dept Resp Med, London SW3 6HP, England

来源：

PULMONARY PHARMACOLOGY & THERAPEUTICS | 2015年 / 35卷

关键词：

Cough; Larynx; Voice; Hypersensitivity; Wheeze; ASTHMA-LIKE SYMPTOMS; EXTRATHORACIC AIRWAY; DYSFUNCTION; HYPERRESPONSIVENESS; RESPONSIVENESS; METHACHOLINE; DISEASE;

D O I：

10.1016/j.pupt.2015.08.008

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Patients with chronic cough often report symptoms arising in the throat, in response to non-specific stimuli. Accordingly, the concept of a 'hypersensitivity' of the larynx in chronic cough has evolved over the past ten years. Patients with cough and laryngeal hypersensitivity frequently report features that overlap other laryngeal dysfunction syndromes, including a tendency for the vocal cords to inappropriately adduct. The mechanisms underlying laryngeal hypersensitivity in chronic cough are currently unclear, however recent studies provide new clinical and physiological techniques to aid detection and monitoring of laryngeal hypersensitivity. This review provides an overview of the current state of knowledge in this field. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：111 / 116

页数：6

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