Bovine leukemia virus relation to human breast cancer: Meta-analysis

被引:12
作者
Gao, Andrew [1 ]
Kouznetsova, Valentina L. [2 ]
Tsigelny, Igor F. [3 ,4 ]
机构
[1] Univ Calif San Diego, SDSC, REHS Program, San Diego, CA USA
[2] San Diego Supercomp Ctr, San Diego, CA USA
[3] Univ Calif San Diego, Dept Neurosci, San Diego, CA 92093 USA
[4] CureMatch Inc, San Diego, CA USA
关键词
breast cancer; bovine leukemia virus; BLV; HTLV; TYPE-1;
D O I
10.1016/j.micpath.2020.104417
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Bovine leukemia virus (BLV) is a virus that infects cattle around the world and is very similar to the human T-cell leukemia virus (HTLV), which causes adult T-cell leukemia/lymphoma (ATL). Recently, presence of BLV DNA and protein was demonstrated in commercial bovine products and in humans. BLV DNA is generally found at higher rates in humans who have or will develop breast cancer, according to research done with subjects from several countries. These findings have led to a hypothesis that BLV transmission plays a role in breast cancer oncogenesis in humans. Here we summarize the current knowledge in the field.
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页数:7
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