New 9, 19-cycloartane triterpenoid from the root of Cimicifuga foetida

被引：6

作者：

Zhu Di-Fan ^{[1
,2
]}

Nian Yin ^{[2
]}

Wang Hai-Yan ^{[2
]}

Zhang Zhi-Run ^{[2
]}

Song Yan-Bo ^{[2
]}

Li Rong-Tao ^{[1
]}

Qiu Ming-Hua ^{[2
]}

机构：

[1] Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650050, Yunnan, Peoples R China

[2] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China

来源：

CHINESE JOURNAL OF NATURAL MEDICINES | 2014年 / 12卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Cimifuga foetida; Ranuncluaceae; 9; 19-Cycloartane triterpene; Acetoxy groups; AERIAL PARTS; CYCLOARTANE TRITERPENOIDS; BLACK COHOSH; GLYCOSIDES; CONSTITUENTS; RACEMOSA; EFFICACY; SAFETY;

D O I：

10.1016/S1875-5364(14)60057-1

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

AIM: To study the 9, 19-cycloartane triterpenes from the roots of Cimicifuga foetida. METHOD: Chromatographic separations by silica gel, CH reversed phase silica gel, and high-performance liquid chromatography (HPLC) were used. All of the structures were elucidated on the basis of spectroscopic analysis and chemical methods. RESULTS: Five 9, 19-cycloartane triterpenes, (3 beta, 12 beta, 15 alpha, 24R)-12, 2'-diacetoxy-24, 25-epoxy-15-hydroxy-16, 23-dione-3-O-alpha-L-arabinopyranoside (1), actein (2), 23-epi-26-deoxyactein (3), asiaticoside B (4), and 12 beta-hydroxycimigenol (5) were isolated from the roots of Cimicifuga foetida. CONCLUSION: Compound 1 is a new triterpene with two acetoxy groups at C-2' and C-12.

引用

页码：294 / 296

页数：3

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