Telomeres and Chronic Heart Failure

被引:0
作者
Drapkina, O. M. [1 ]
Shepel, R. N. [1 ]
机构
[1] Sechenovs First Moscow State Med Univ, Moscow 119992, Russia
关键词
chronic heart failure; left ventricular diastolic dysfunction; diastolic heart failure; the left ventricle; normal left ventricular ejection fraction; remodeling; fibrosis; telomeres; aging; AGE; ACTIVATION; RESPONSES; DEATH; CELLS;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
With age, a person's cardio-vascular system changes gradually formed at different functional levels, which are the basis for the development of chronic heart failure. While aging itself does not lead to chronic heart failure, it is likely that age-related changes in the human body can accelerate the time onset of signs and symptoms of the disease. Different groups of patients start time and rate of progression of heart failure is extremely constant. Recently, particular attention is paid to the study of diastolic heart failure because of the high prevalence and some of the difficulties in diagnosis and treatment.
引用
收藏
页码:60 / +
页数:8
相关论文
共 28 条
[1]  
[Anonymous], REITING KRUPNEISHIKH
[2]   Cardiomyocyte death and renewal in the normal and diseased heart [J].
Buja, Louis Maximilian ;
Vela, Deborah .
CARDIOVASCULAR PATHOLOGY, 2008, 17 (06) :349-374
[3]   Age-associated changes in cardiac matrix and integrins [J].
Burgess, ML ;
McCrea, JC ;
Hedrick, HL .
MECHANISMS OF AGEING AND DEVELOPMENT, 2001, 122 (15) :1739-1756
[4]   Senescence and death of primitive cells and myocytes lead to premature cardiac aging and heart failure [J].
Chimenti, C ;
Kajstura, J ;
Torella, D ;
Urbanek, K ;
Heleniak, H ;
Colussi, C ;
Di Meglio, F ;
Nadal-Ginard, B ;
Frustaci, A ;
Leri, A ;
Maseri, A ;
Anversa, P .
CIRCULATION RESEARCH, 2003, 93 (07) :604-613
[5]   Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+study [J].
Collerton, Joanna ;
Martin-Ruiz, Carmen ;
Kenny, Antoinette ;
Barrass, Karen ;
von Zglinicki, Thomas ;
Kirkwood, Tom ;
Keavney, Bernard .
EUROPEAN HEART JOURNAL, 2007, 28 (02) :172-176
[6]   Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction [J].
Dhahbi, JM ;
Tsuchiya, T ;
Kim, HJ ;
Mote, PL ;
Spindler, SR .
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2006, 61 (03) :218-231
[7]   RESOLVED AND UNRESOLVED ISSUES IN THE PREVENTION AND TREATMENT OF CORONARY-ARTERY DISEASE - A WORKSHOP CONSENSUS STATEMENT [J].
DZAU, V ;
BRAUNWALD, E .
AMERICAN HEART JOURNAL, 1991, 121 (04) :1244-1263
[8]   LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS [J].
HAYFLICK, L .
EXPERIMENTAL CELL RESEARCH, 1965, 37 (03) :614-&
[9]  
Huzen J, 2008, Ned Tijdschr Geneeskd, V152, P1265
[10]  
Kitzman Dalane W, 2002, Heart Fail Rev, V7, P17