Bronsted Acid-Catalyzed Straightforward Synthesis of Benzo[b]carbazoles from 2,3-Unsubstituted Indoles

被引：41

作者：

Suarez, Anisley ^{[1
]}

Garcia-Garcia, Patricia ^{[1
]}

Fernandez-Rodriguez, Manuel A. ^{[1
]}

Sanz, Roberto ^{[1
]}

机构：

[1] Univ Burgos, Fac Ciencias, Dept Quim, Area Quim Organ, Burgos 09001, Spain

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2014年 / 356卷 / 2-3期

关键词：

1; 2-alkyl shift; benzo[b]carbazoles; BrOnsted acid catalysis; heterocycles; synthetic methods; ACTIVE CARBAZOLE ALKALOIDS; FRIEDEL-CRAFTS ALKYLATION; ENANTIOSELECTIVE SYNTHESIS; CYCLOADDITION REACTIONS; HIGHLY EFFICIENT; DOMINO REACTIONS; ELLIPTICINE; DERIVATIVES; MIGRATION; SEQUENCE;

D O I：

10.1002/adsc.201300868

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Described is a general and efficient synthesis of valuable benzo[b]carbazoles by BrOnsted acid-catalyzed reactions between simple C-2,C-3-unsubstituted indoles and ortho-[-(hydroxy)benzyl]benzaldehyde acetals. Highly selective migration processes are involved as key steps in the overall cascade sequence that involves the one-pot formation of two new bonds and a cycle in a regioselective fashion.

引用

页码：374 / 382

页数：9

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