VILSMEIER REAGENT: AN EFFICIENT REAGENT FOR THE TRANSFORMATION OF 2-AMINOBENZAMIDES INTO QUINAZOLIN-4(3H)-ONE DERIVATIVES

被引：27

作者：

Farzipour, Soghra ^{[1
]}

Saeedi, Mina ^{[2
]}

Mahdavi, Mohammad ^{[2
]}

Yavari, Hossein ^{[2
]}

Mirzahekmati, Mohammadreza ^{[2
]}

Ghaemi, Nasser ^{[1
]}

Foroumadi, Alireza ^{[2
]}

Shafiee, Abbas ^{[2
]}

机构：

[1] Univ Tehran, Sch Chem, Coll Sci, Tehran, Iran

[2] Univ Tehran Med Sci, Dept Med Chem, Fac Pharm & Pharmaceut Sci, Res Ctr, Tehran 14176, Iran

来源：

SYNTHETIC COMMUNICATIONS | 2014年 / 44卷 / 04期

基金：

美国国家科学基金会;

关键词：

2-Aminobenzamides; heterocycles; isotoic anhydride; 4(3H)-quinazolinones; Vilsmeier reagent; PLATELET ANTIAGGREGANT ACTIVITY; SOLVENT-FREE CONDITIONS; IN-VITRO; CYCLIZATION; CONVENIENT; IODINE; AGENTS;

D O I：

10.1080/00397911.2013.811528

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Clean and easy preparation of quinazolin-4(3H)-one derivatives using 2-aminobenzamides and Vilsmeier reagent is described. 2-Aminobenzamides were converted into the corresponding quinazolinones under mild and efficient conditions, in good yields without undesirable by-products. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) for the following free supplemental resource(s): Full experimental and spectral details.]

引用

页码：481 / 487

页数：7

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