Autoimmune enteropathy in an adult with autoimmune multisystemic involvement

被引:22
作者
Casis, B
Fernández-Vázquez, I
Barnardos, E
Saiz, A
Ballestín, C
Morillas, JD
Colina, F
Solís-Herruzo, JA
机构
[1] Hosp Univ 12 Octubre, Dept Gastroenterol, Serv Med Aparato Digest, ES-28041 Madrid, Spain
[2] Hosp Univ 12 Octubre, Dept Pathol, ES-28041 Madrid, Spain
关键词
autoimmune enteropathy; autoimmunity; intractable diarrhoea;
D O I
10.1080/003655202320378185
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
We describe the case of a 58-year-old woman with autoimmune enteropathy associated with thyroiditis, gastritis, transitory neutropenia, sicca syndrome and severe axonal polyneuropathy of autoimmune origin. Enterocyte autoantibodies were not detected. However, predisposition to autoimmune disease was indicated by the presence of high titres of anti-gastri c parietal cell, anti-thyroglobulin, anti-thyroid peroxidase and anti-neutrophil antibodies. CD4+ and CD8+ lymphocytes were equally distributed in the lamina propria of the small intestine, but CD8+ cells were highly represented among intraepithelial lymphocytes.
引用
收藏
页码:1012 / 1016
页数:5
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