Arsenic trioxide suppresses acute graft-versus-host disease by activating the Nrf2/HO-1 pathway in mice

被引:10
作者
Hu, Xiaoli [1 ]
Li, Liwei [1 ]
Yan, Sai [1 ]
Li, Zhiqiang [1 ]
机构
[1] Shanghai Jiao Tong Univ, Affiliated Peoples Hosp 6, Dept Blood Transfus, Shanghai, Peoples R China
关键词
acute graft-versus-host disease; arsenic trioxide; T cell subsets; cytokines; Nrf2; HO-1; CELLS;
D O I
10.1111/bjh.15982
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:E145 / E148
页数:4
相关论文
共 10 条
[1]   An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation .1. The roles of minor H antigens and endotoxin [J].
Cooke, KR ;
Kobzik, L ;
Martin, TR ;
Brewer, J ;
Delmonte, J ;
Crawford, JM ;
Ferrara, JLM .
BLOOD, 1996, 88 (08) :3230-3239
[2]   2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells [J].
Gong, Xuezhong ;
Ivanov, Vladimir N. ;
Hei, Tom K. .
ARCHIVES OF TOXICOLOGY, 2016, 90 (09) :2187-2200
[3]   Nobiletin attenuates lipopolysaccharide/D-galactosamine-induced liver injury in mice by activating the Nrf2 antioxidant pathway and subsequently inhibiting NF-κB-mediated cytokine production [J].
He, Zhenxing ;
Li, Xuanfei ;
Chen, Rao ;
He, Kun ;
Liu, Yiming ;
Gong, Junhua ;
Gong, Jianping .
MOLECULAR MEDICINE REPORTS, 2016, 14 (06) :5595-5600
[4]   Arsenic Trioxide Prevents Murine Sclerodermatous Graft-versus-Host Disease [J].
Kavian, Niloufar ;
Marut, Wioleta ;
Servettaz, Amelie ;
Laude, Helene ;
Nicco, Carole ;
Chereau, Christiane ;
Weill, Bernard ;
Batteux, Frederic .
JOURNAL OF IMMUNOLOGY, 2012, 188 (10) :5142-5149
[5]   New strategies for preventing graft-versus-host disease [J].
Murphy, WJ ;
Blazar, BR .
CURRENT OPINION IN IMMUNOLOGY, 1999, 11 (05) :509-515
[6]   Epigallocatechin gallate induces expression of heme oxygenase-1 in endothelial cells via p38 MAPK and Nrf-2 that suppresses proinflammatory actions of TNF-α [J].
Pullikotil, Philomena ;
Chen, Hui ;
Muniyappa, Ranganath ;
Greenberg, Cynthia C. ;
Yang, Shutong ;
Reiter, Chad E. N. ;
Lee, Ji-Won ;
Chung, Jay H. ;
Quon, Michael J. .
JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2012, 23 (09) :1134-1145
[7]   Th2 Skewing by Activation of Nrf2 in CD4+ T Cells [J].
Rockwell, Cheryl E. ;
Zhang, Mingcai ;
Fields, Patrick E. ;
Klaassen, Curtis D. .
JOURNAL OF IMMUNOLOGY, 2012, 188 (04) :1630-1637
[8]  
SYKES M, 1993, J IMMUNOL, V150, P197
[9]  
UENAKA A, 1989, TRANSPLANT P, V21, P3031
[10]   Arsenic Trioxide Attenuated the Rejection of Major Histocompatibility Complex Fully-Mismatched Cardiac Allografts in Mice [J].
Yan, S. ;
Zhang, Q. Y. ;
Zhou, B. ;
Xue, L. ;
Chen, H. ;
Wang, Y. ;
Zheng, S. S. .
TRANSPLANTATION PROCEEDINGS, 2009, 41 (05) :1855-1858