The Design of Digital Circuit Based on DNA Strand Displacement Reaction

被引:1
作者
Wang, Zicheng [1 ]
Cai, Zijie [1 ]
Sun, Zhonghua [1 ]
Wang, Yanfeng [1 ]
Cui, Guangzhao [1 ]
机构
[1] Zhengzhou Univ Light Ind, Coll Elect & Informat Engn, Henan Key Lab Informat Based Elect Appliances, 5 Dongfeng Rd, Zhengzhou 450002, Peoples R China
来源
BIO-INSPIRED COMPUTING - THEORIES AND APPLICATIONS, BIC-TA 2015 | 2015年 / 562卷
关键词
DNA strand displacement reaction; Encoder; Decoder; Visual DSD; NEURAL P SYSTEMS; SYNAPSES WORKING; COMPUTATION; NANOTECHNOLOGY; RULES;
D O I
10.1007/978-3-662-49014-3_41
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
Because of its outstanding advantages, DNA strand displacement (DSD) reaction has been widely used for signals processing and molecular logic circuit constructing. Two digital logic circuits are constructed in this paper. One is the encoder circuit with four inputs and two outputs, and the other is the decoder circuit with two inputs and four outputs. Finally, the circuits can be programmed and simulated with the software Visual DSD. The simulated results based on DSD show that the molecular circuits constructed in this paper is reliable and effective, which has wide prospects in logical circuits and nano electronics study.
引用
收藏
页码:456 / 464
页数:9
相关论文
共 34 条
[1]  
[Anonymous], 2012, QUANTUM MATTER, DOI DOI 10.1166/QM.2012.1012
[2]   An autonomous molecular computer for logical control of gene expression [J].
Benenson, Y ;
Gil, B ;
Ben-Dor, U ;
Adar, R ;
Shapiro, E .
NATURE, 2004, 429 (6990) :423-429
[3]   Origins and Mechanisms of miRNAs and siRNAs [J].
Carthew, Richard W. ;
Sontheimer, Erik J. .
CELL, 2009, 136 (04) :642-655
[4]  
Eckhoff G., 2010, J Syst Chem, V1, P13, DOI [DOI 10.1186/1759-2208-1-13, 10.1186/1759-2208-1-13]
[5]   MicroRNA biogenesis: Coordinated cropping and dicing [J].
Kim, VN .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2005, 6 (05) :376-385
[6]   Abstractions for DNA circuit design [J].
Lakin, Matthew R. ;
Youssef, Simon ;
Cardelli, Luca ;
Phillips, Andrew .
JOURNAL OF THE ROYAL SOCIETY INTERFACE, 2012, 9 (68) :470-486
[7]   Visual DSD: a design and analysis tool for DNA strand displacement systems [J].
Lakin, Matthew R. ;
Youssef, Simon ;
Polo, Filippo ;
Emmott, Stephen ;
Phillips, Andrew .
BIOINFORMATICS, 2011, 27 (22) :3211-3213
[8]   Designed two-dimensional DNA Holliday junction arrays visualized by atomic force microscopy [J].
Mao, CD ;
Sun, WQ ;
Seeman, NC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (23) :5437-5443
[9]   Logical computation using algorithmic self-assembly of DNA triple-crossover molecules [J].
Mao, CD ;
LaBean, TH ;
Reif, JH ;
Seeman, NC .
NATURE, 2000, 407 (6803) :493-496
[10]  
Pan L., 2014, PLOS ONE, V9, P94664