(η6-Arene)RuII/Chiral SN Ligand: A Novel Bifunctional Catalyst System for Asymmetric Transfer Hydrogenation of Aromatic Ketones

被引：27

作者：

Ito, Masato ^{[1
]}

Shibata, Yuji ^{[1
]}

Watanabe, Akira ^{[1
]}

Ikariya, Takao ^{[1
]}

机构：

[1] Tokyo Inst Technol, Grad Sch Sci & Engn, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan

来源：

SYNLETT | 2009年 / 10期

关键词：

RuCl2(eta(6)-arene)](2); protic aminothiol ligand; asymmetric transfer hydrogenation; aromatic ketone; bifunctionality; CP-ASTERISK-RU(PN) COMPLEXES; MOLECULAR CATALYSTS; FORMIC-ACID; ALCOHOLS; RUTHENIUM; SULFIDES; BEARING; FUNCTIONALITIES; RACEMIZATION;

D O I：

10.1055/s-0029-1217349

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A binary catalyst system of [RuCl2(eta(6)-arene)](2) and a erotic aminothiol (SN) ligand has been found to promote hydrogen transfer between alcohols and carbonyl compounds. The chiral catalyst system with the pipecolinol-derived chiral SN ligand displays excellent stereoselectivity in the asymmetric transfer hydrogenation of aromatic ketones using HCO2H-Et3N. Novel unsymmetrical bis(thiolate)-bridged binuclear complex, which is relevant to the generation of catalytically active species, has been synthesized and structurally characterized.

引用

页码：1621 / 1626

页数：6

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