An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

被引：25
作者：
Yan, Liqiang [1 ]
Kong, Zhineng [1 ]
Shen, Wei [1 ]
Du, Wenqi [1 ]
Zhou, Yan [1 ]
Qi, Zhengjian [1 ]
机构：
[1] Southeast Univ, Coll Chem & Chem Engn, Nanjing 211189, Jiangsu, Peoples R China
来源：
RSC ADVANCES | 2016年 / 6卷 / 07期
关键词：
SELECTIVE DETECTION; HOMOCYSTEINE; MITOCHONDRIA; PLASMA; THIOLS; SENSOR; CELLS;
D O I：
10.1039/c5ra22245a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F-450/F-575) (R-2 = 0.9922) versus Cys concentration in the range of 1-13 mu M was obtained.
引用
收藏
页码：5636 / 5640
页数：5
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