This paper tries to assess the application of quantitative approaches and hypothesis testing using 'Path Analysis' technique as an alternative approach to the performance of managerial leadership that can be used to achieve the goals in finding and determine the factors that influence and support the managerial performance leadership. Analysis of the data that is used in this study consisted of descriptive analysis to look at the characteristics of the population which is netted in the study and path analysis. The sample of technique in this study is using proportionate stratified random sampling technique. The number of samples, which is used as the respondent in the unit of analysis of this study, is 130 head of private universities around Kopertis region II, southern Sumatran. The results of data analysis show that (1) the leadership of a significant and positive impact on managerial performance, (2) empowerment of human resources directly affects on managerial performance, (3) governance directly affects managerial performance, (4) the leadership of a significant and positive impact on governance, (5) directly affects the organizational culture of good governance, (6) human resources empowerment significant and positive impact on governance.