Penetrating the Blood-Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles

被引：82

作者：

Ali, Iqbal Unnisa ^{[1
]}

Chen, Xiaoyuan ^{[1
]}

机构：

[1] Natl Inst Biomed Imaging & Bioengn, Lab Mol Imaging & Nanomed, NIH, Bethesda, MD 20892 USA

来源：

ACS NANO | 2015年 / 9卷 / 10期

关键词：

NERVOUS-SYSTEM; CANCER; NANOPARTICLES; MACROPHAGES; TRANSPORT; GROWTH; CELLS; SIRNA;

D O I：

10.1021/acsnano.5b05341

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Multifunctional nanoplatforms combining versatile therapeutic modalities with a variety of imaging options have the potential to diagnose, monitor, and treat brain diseases. The promise of nanotechnology can only be realized by the simultaneous development of innovative brain-targeting delivery vehicles capable of penetrating the blood brain barrier without compromising its structural integrity.

引用

页码：9470 / 9474

页数：5

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