Penetrating the Blood-Brain Barrier: Promise of Novel Nanoplatforms and Delivery Vehicles

被引：78
作者：
Ali, Iqbal Unnisa [1 ]
Chen, Xiaoyuan [1 ]
机构：
[1] Natl Inst Biomed Imaging & Bioengn, Lab Mol Imaging & Nanomed, NIH, Bethesda, MD 20892 USA
来源：
ACS NANO | 2015年 / 9卷 / 10期
关键词：
NERVOUS-SYSTEM; CANCER; NANOPARTICLES; MACROPHAGES; TRANSPORT; GROWTH; CELLS; SIRNA;
D O I：
10.1021/acsnano.5b05341
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Multifunctional nanoplatforms combining versatile therapeutic modalities with a variety of imaging options have the potential to diagnose, monitor, and treat brain diseases. The promise of nanotechnology can only be realized by the simultaneous development of innovative brain-targeting delivery vehicles capable of penetrating the blood brain barrier without compromising its structural integrity.
引用
收藏
页码：9470 / 9474
页数：5
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