Synthesis and structural features of copper(II) complexes of benzoic acid and methyl substituted benzoic acid hydrazides and X-ray structure of Cu[C6H5CONHNH2]2(NO3)2

The synthesis, spectroscopic, magnetic and biological activities of copper(II) complexes of benzoic acid hydrazides (BAH) and o, m, and p-substituted methylbenzoic acid hydrazides (MBAH) and the single crystal X-ray structure for bis(benzoic acid hydrazide)copper(II) nitrate {Cu[BAH](2)(NO3)(2)} (BAH = Benzoic acid hydrazide) are reported. The composition of the ligands was established by elemental analyses, H-1 NMR, and GC-MS. Magnetic susceptibility, electronic and infrared spectral data are consistent with a mononuclear square-planar geometry with bidentate coordination of the hydrazide ligands to give essentially a CUN2O2 chromophore. Cu[BAH](2)(NO3)(2) crystallizes from methanol solution under ambient temperature in a monoclinic system with a P2(1)/c space system. The copper atom has a nearly regular, four-coordinated, square-planar arrangement with the nitrate anions being uncoordinated in the crystal lattice. The compounds did not show significant activity against selected bacteria and fungi.