DNA vaccines against anthrax

被引：14

作者：

Galloway, DR ^{[1
]}

Baillie, L ^{[1
]}

机构：

[1] USN, Med Res Ctr, Biodef Res Directorate, Silver Spring, MD 20903 USA

来源：

EXPERT OPINION ON BIOLOGICAL THERAPY | 2004年 / 4卷 / 10期

关键词：

anthrax; Bacillus anthracis; DNA vaccine; genetic immunisation; lethal factor; protective antigen;

D O I：

10.1517/14712598.4.10.1661

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

DNA vaccination is vaccination at its simplest. Due to renewed interest in vaccination against anthrax and other biothreat agents, a genetic immunisation approach offers attractive possibilities for rapid, responsive vaccine development. DNA vaccination against anthrax is an active area of research showing promising results at present, which in the short-term and in the future could form the basis for new advances in multi-agent vaccine development. The anthrax 'model' constitutes an important experimental system for genetic immunisation technology development.

引用

页码：1661 / 1667

页数：7

共 46 条

[1]

[Anonymous], 2002, ANTHRAX VACCINE IS I

[2] The development of new vaccines against Bacillus anthracis [J].

Baillie, L .

JOURNAL OF APPLIED MICROBIOLOGY, 2001, 91 (04) :609-613

[3] Bacillus anthracis, a bug with attitude! [J].

Baillie, L ;

Read, TD .

CURRENT OPINION IN MICROBIOLOGY, 2001, 4 (01) :78-81

[4] Ebola and Marburg virus-like particles activate human myeloid dendritic cells [J].

Bosio, CM ;

Moore, BD ;

Warfield, KL ;

Ruthel, G ;

Mohamadzadeh, M ;

Aman, MJ ;

Bavari, S .

VIROLOGY, 2004, 326 (02) :280-287

[5]

CHAPMAN G, 2004, ASM BIOD M BALT MD U

[6] Biological warfare - A historical perspective [J].

Christopher, GW ;

Cieslak, TJ ;

Pavlin, JA ;

Eitzen, EM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 278 (05) :412-417

[7] DNA-BASED IMMUNIZATION INDUCES CONTINUOUS SECRETION OF HEPATITIS-B SURFACE-ANTIGEN AND HIGH-LEVELS OF CIRCULATING ANTIBODY [J].

DAVIS, HL ;

MICHEL, ML ;

WHALEN, RG .

HUMAN MOLECULAR GENETICS, 1993, 2 (11) :1847-1851

[8] Anthrax [J].

Dixon, TC ;

Meselson, M ;

Guillemin, J ;

Hanna, PC .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 341 (11) :815-826

[9]

Donnelly J J, 1998, Dev Biol Stand, V95, P43

[10] Rabies DNA vaccine in the horse: strategies to improve serological responses [J].

Fischer, L ;

Minke, J ;

Dufay, N ;

Baudu, P ;

Audonnet, JC .

VACCINE, 2003, 21 (31) :4593-4596

← 1 2 3 4 5 →