Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

被引:29
作者
Chung, Jin-Hwan [1 ]
Kim, Young Kyung [3 ]
Kim, Kyo-Han [1 ,2 ]
Kwon, Tae-Yub [1 ,2 ]
Vaezmomeni, Seyede Ziba [5 ]
Samiei, Mohammad [5 ]
Aghazadeh, Marzyeh [5 ]
Davaran, Soodabeh [4 ]
Mahkam, Mehrdad [5 ]
Asadi, Ghale [5 ]
Akbarzadeh, Abolfazl [4 ]
机构
[1] Kyungpook Natl Univ, Dept Med & Biol Engn, Grad Sch, Daegu 700412, South Korea
[2] Kyungpook Natl Univ, Sch Dent, Dept Dent Biomat, Daegu 700412, South Korea
[3] Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, Daegu 700412, South Korea
[4] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran
[5] Tabriz Univ Med Sci, Sch Dent, Dept Endodont, Tabriz, Iran
基金
新加坡国家研究基金会;
关键词
biomedical applications; hydroxyapatite; inorganic-organic nanocomposite; natural polymers; COATED MAGNETIC NANOPARTICLES; IN-VITRO EVALUATION; GENE-EXPRESSION; COMPOSITE-MATERIALS; TISSUE; BONE; INHIBITION; HYDROGELS; CURCUMIN; COATINGS;
D O I
10.3109/21691401.2014.944644
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)(2).4H(2)O and diammonium hydrogen phosphate (NH4)(2)HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).
引用
收藏
页码:277 / 284
页数:8
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