Synthesis, characterization, biocompatibility of hydroxyapatite-natural polymers nanocomposites for dentistry applications

被引：29

作者：

Chung, Jin-Hwan ^{[1
]}

Kim, Young Kyung ^{[3
]}

Kim, Kyo-Han ^{[1
,2
]}

Kwon, Tae-Yub ^{[1
,2
]}

Vaezmomeni, Seyede Ziba ^{[5
]}

Samiei, Mohammad ^{[5
]}

Aghazadeh, Marzyeh ^{[5
]}

Davaran, Soodabeh ^{[4
]}

Mahkam, Mehrdad ^{[5
]}

Asadi, Ghale ^{[5
]}

Akbarzadeh, Abolfazl ^{[4
]}

机构：

[1] Kyungpook Natl Univ, Dept Med & Biol Engn, Grad Sch, Daegu 700412, South Korea

[2] Kyungpook Natl Univ, Sch Dent, Dept Dent Biomat, Daegu 700412, South Korea

[3] Kyungpook Natl Univ, Sch Dent, Dept Conservat Dent, Daegu 700412, South Korea

[4] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz, Iran

[5] Tabriz Univ Med Sci, Sch Dent, Dept Endodont, Tabriz, Iran

来源：

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2016年 / 44卷 / 01期

基金：

新加坡国家研究基金会;

关键词：

biomedical applications; hydroxyapatite; inorganic-organic nanocomposite; natural polymers; COATED MAGNETIC NANOPARTICLES; IN-VITRO EVALUATION; GENE-EXPRESSION; COMPOSITE-MATERIALS; TISSUE; BONE; INHIBITION; HYDROGELS; CURCUMIN; COATINGS;

D O I：

10.3109/21691401.2014.944644

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)(2).4H(2)O and diammonium hydrogen phosphate (NH4)(2)HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).

引用

页码：277 / 284

页数：8

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